Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | OSBP | P22059 | 8/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31545427 | 1.00 | PDE5A (0.38) | PDE5ATP53CYP3A4OSBPCYP19A1 | |
| SCHEMBL31545958 | 0.88 | CYP19A1 (0.39) | PDE5ATP53CYP3A4OSBPCYP19A1 | |
| SCHEMBL31545700 | 0.82 | PDE5A (0.40) | PDE5ATP53CYP3A4CYP19A1CTSB | |
| SCHEMBL24212285 | 0.82 | PDE5A (0.40) | PDE5ATP53CYP3A4CYP19A1CTSB | |
| SCHEMBL24212514 | 0.81 | CNR1 (0.44) | PDE5ATP53CYP3A4OSBPCYP19A1 | |
| SCHEMBL3246245 | 0.78 | ALDH1A1 (0.49) | PDE5AOSBPCYP19A1CTSBMALT1 | |
| SCHEMBL31545960 | 0.78 | ALDH1A1 (0.49) | PDE5AOSBPCYP19A1CTSBMALT1 | |
| SCHEMBL24212288 | 0.77 | PDE5A (0.37) | PDE5ATP53CYP3A4OSBPCYP19A1 | |
| SCHEMBL24212287 | 0.75 | CYP19A1 (0.39) | PDE5ATP53CYP3A4OSBPCYP19A1 | |
| SCHEMBL24212289 | 0.75 | AKT1 (0.38) | PDE5ATP53CYP3A4CYP19A1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017482-A1 | Synthetic Antibacterial Compounds and Uses Thereof | UNIV MCMASTER (CA) | 2022-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220017482-A1 | Synthetic Antibacterial Compounds and Uses Thereof | SPOUT1, NRDC, MRPL21 | PDE5A 2426/4885TP53 3468/4885CYP3A4 2781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.