Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 4/20 | 1.00 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.54 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.54 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.54 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.54 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.54 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.54 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.54 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.54 |
| ▸ | GALE | Q14376 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SULT1E1 | P49888 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 5/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24212694 | 0.85 | NR1H4 (1.00) | NR1H4ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL20640640 | 0.79 | NR1H4 (0.65) | NR1H4ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL16984794 | 0.71 | NR1H4 (0.54) | NR1H4ALDH1A1MAPTCYP3A4CETP | |
| SCHEMBL29836725 | 0.71 | NR1H4 (0.55) | NR1H4ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL16556735 | 0.71 | NR1H4 (0.53) | NR1H4ALDH1A1MAPTCYP3A4CETP | |
| SCHEMBL15874208 | 0.66 | DUSP3 (0.63) | NR1H4CETPCDC25APTPN1DUSP3 | |
| SCHEMBL29412257 | 0.65 | LMNA (0.55) | NR1H4ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL15874634 | 0.65 | CETP (0.57) | NR1H4ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL13446720 | 0.65 | ALDH1A1 (0.72) | NR1H4ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL13446726 | 0.65 | ALDH1A1 (0.72) | NR1H4ATP1A1ATP1B1ATP1A3ATP1B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220016136-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIVER DISORDERS | VIKING THERAPEUTICS, INC. | 2022-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220016136-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIVER DISORDERS | FABP1, SLC10A1, TSHR | NR1H4 11/4885ATP1A1 2660/4885ATP1B1 3073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.