Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 16/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30516575 | 1.00 | ALDH1A1 (0.39) | ALDH1A1POLBSMN1; SMN2P2RY12MEN1 | |
| SCHEMBL30412329 | 0.86 | TP53 (0.35) | P2RY12KMT2A | |
| SCHEMBL24215466 | 0.84 | P2RY12 (0.38) | P2RY12MEN1KMT2A | |
| SCHEMBL24215660 | 0.81 | MAPK1 (0.35) | ALDH1A1P2RY12 | |
| SCHEMBL24215654 | 0.80 | P2RY12 (0.39) | P2RY12 | |
| SCHEMBL30516630 | 0.80 | ALDH1A1 (0.40) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL24215526 | 0.80 | ALDH1A1 (0.40) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL30413021 | 0.80 | P2RY12 (0.39) | P2RY12 | |
| SCHEMBL24215658 | 0.80 | SCN10A (0.37) | — | |
| SCHEMBL30411369 | 0.80 | SCN10A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528862-A | Compounds and compositions for the treatment of diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2023-08-01 | — | — | CN | disclosed |
| EP-4182028-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM Due, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022015957-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2022-01-20 | — | — | WO | disclosed |
| WO-2022015957-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2022-01-20 | — | — | WO | disclosed |