Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24215526 | 1.00 | ALDH1A1 (0.40) | ALDH1A1POLBSMN1; SMN2P2RX7KDM1A | |
| SCHEMBL30412536 | 0.86 | POLB (0.34) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL30516575 | 0.80 | ALDH1A1 (0.39) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL24215580 | 0.80 | ALDH1A1 (0.39) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL24214081 | 0.78 | MAPK1 (0.37) | ALDH1A1POLBP2RX7CYP2C9 | |
| SCHEMBL30516596 | 0.78 | MAPK1 (0.37) | ALDH1A1POLBP2RX7CYP2C9 | |
| SCHEMBL24215525 | 0.76 | HDAC6 (0.33) | P2RX7KDM1AMAOBMAPK14 | |
| SCHEMBL24214080 | 0.76 | HCAR2 (0.36) | — | |
| SCHEMBL20332482 | 0.74 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL24215529 | 0.72 | RORC (0.33) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528862-A | Compounds and compositions for the treatment of diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2023-08-01 | — | — | CN | disclosed |