SCHEMBL24215967

SCHEMBL24215967

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4oc5cc(-c6ccc7c(ccc8ccccc87)c6)ccc5c4c3)n2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 7/20 0.44
▸ ALDH1A1 P00352 6/20 0.44
▸ MAPT P10636 4/20 0.44
▸ HPGD P15428 3/20 0.44
▸ HSD17B10 Q99714 3/20 0.44
▸ TSHR P16473 2/20 0.44
▸ ALOX15 P16050 1/20 0.44
▸ CASP1 P29466 1/20 0.44
▸ CASP7 P55210 1/20 0.44
▸ GLA P06280 2/20 0.43
▸ HTT P42858 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ KMT2A Q03164 2/20 0.42
▸ MAPK1 P28482 1/20 0.42
▸ GAA P10253 2/20 0.41
▸ GPR55 Q9Y2T6 1/20 0.40
▸ HCRTR1 O43613 1/20 0.40
▸ HNF4A P41235 1/20 0.40
▸ SMN1; SMN2 Q16637 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24216922 1.00 KDM4E (0.44) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL24217172 0.96 KDM4E (0.47) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL15964277 0.95 KDM4E (0.44) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL24215897 0.94 MAPT (0.43) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL25621650 0.93 KDM4E (0.45) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL24473046 0.93 KDM4E (0.45) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL21450405 0.93 HCRTR1 (0.43) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL24306928 0.93 AHR (0.42) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL24216362 0.92 KMT2A (0.46) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL26217282 0.92 HCRTR1 (0.41) KDM4EALDH1A1MAPTHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-09-21 — — US disclosed
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-09-21 — — US disclosed
US-20230263054-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-08-17 — — US disclosed
US-20230263054-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-08-17 — — US disclosed
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-06-01 — — US disclosed
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-06-01 — — US disclosed
WO-2022015084-A1 ORGANIC LIGHT-EMITTING ELEMENT 주식회사 엘지화학 2022-01-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CYP1A2, CYP1A1 KDM4E 2372/4885ALDH1A1 14/4885MAPT 766/4885
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, CYP1A1 KDM4E 3655/4885ALDH1A1 7/4885MAPT 1437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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