⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1938635 | 0.98 | — | — | |
| SCHEMBL849426 | 0.70 | — | — | |
| SCHEMBL2058641 | 0.70 | — | — | |
| SCHEMBL312270 | 0.70 | — | — | |
| Fluoxidine SCHEMBL1369498 | 0.70 | — | — | |
| SCHEMBL1771094 | 0.70 | — | — | |
| SCHEMBL88588 | 0.70 | — | — | |
| SCHEMBL27189368 | 0.69 | ALDH1A1 (0.38) | — | |
| SCHEMBL17850500 | 0.69 | ALDH1A1 (0.33) | — | |
| Bromide SCHEMBL1938531 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067126-A1 | PYRIDONE COMPOUNDS AND PREPARATION METHOD THEREFOR, AND APPLICATION | 深圳信立泰药业股份有限公司 | 2025-04-03 | — | — | WO | disclosed |
| US-11731977-B2 | SGC stimulators | CYCLERION THERAPEUTICS, INC. (US) | 2023-08-22 | — | — | US | disclosed |
| US-11731977-B2 | SGC stimulators | CYCLERION THERAPEUTICS, INC. (US) | 2023-08-22 | — | — | US | disclosed |
| EP-3872080-B1 | FUSED BICYCLIC SGC STIMULATORS | CYCLERION THERAPEUTICS INC (US) | 2023-08-16 | — | — | EP | disclosed |
| US-20220017515-A1 | sGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2022-01-20 | — | — | US | disclosed |
| US-20220009937-A1 | sGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2022-01-13 | — | — | US | disclosed |
| US-11180493-B2 | SGC stimulators | CYCLERION THERAPEUTICS, INC. (US) | 2021-11-23 | — | — | US | disclosed |
| EP-3507291-B1 | FUSED BICYCLIC SGC STIMULATORS | CYCLERION THERAPEUTICS INC (US) | 2021-05-26 | — | — | EP | disclosed |
| US-20210087198-A1 | sGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2021-03-25 | — | — | US | disclosed |
| US-10858363-B2 | SGC stimulators | CYCLERION THERAPEUTICS, INC. (US) | 2020-12-08 | — | — | US | disclosed |
| WO-2004112480-A2 | TRIAZOLOPYRIMIDINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-12-29 | — | — | WO | disclosed |
| WO-2004113342-A1 | TRIAZOLOPYRIMIDINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-12-29 | — | — | WO | disclosed |
| WO-2004113341-A2 | FUNGICIDAL TRIAZOLOPYRIMIDINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-12-29 | — | — | WO | disclosed |
| WO-2004108727-A1 | TRIAZOLOPYRIMIDINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-12-16 | — | — | WO | disclosed |
| US-20040152690-A1 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. | 2004-08-05 | — | — | US | disclosed |
| WO-2004035549-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR LIGANDS | AMGEN INC. (US) | 2004-04-29 | — | — | WO | disclosed |
| EP-0708758-B1 | METHOD OF PREPARING 5-CHLORO-4-HYDROXYPYRIMIDINES, 2-CHLORENAMINES AS INTERMEDIATES IN THE METHOD, AND USE OF THE COMPOUNDS THUS PREPARED | HOECHST SCHERING AGREVO GMBH (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5523404-A | Process for preparing 5-chloro-4-hydroxypyrimidines | HOECHST SCHERING AGREVO GMBH (DE) | 1996-06-04 | — | — | US | disclosed |
| EP-0708758-A1 | METHOD OF PREPARING 5-CHLORO-4-HYDROXYPYRIMIDINES, 2-CHLORENAMINES AS INTERMEDIATES IN THE METHOD, AND USE OF THE COMPOUNDS THUS PREPARED | Hoechst Schering AgrEvo GmbH (DE) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995001963-A1 | METHOD OF PREPARING 5-CHLORO-4-HYDROXYPYRIMIDINES, 2-CHLORENAMINES AS INTERMEDIATES IN THE METHOD, AND USE OF THE COMPOUNDS THUS PREPARED | HOECHST SCHERING AGREVO GMBH (DE) | 1995-01-19 | — | — | WO | disclosed |