⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoxidine SCHEMBL1369498 | 0.70 | — | — | |
| SCHEMBL849426 | 0.70 | — | — | |
| SCHEMBL2058641 | 0.70 | — | — | |
| SCHEMBL2421685 | 0.70 | — | — | |
| SCHEMBL1771094 | 0.70 | — | — | |
| SCHEMBL25435625 | 0.70 | ALDH1A1 (0.39) | — | |
| SCHEMBL17461712 | 0.70 | — | — | |
| SCHEMBL12182658 | 0.70 | ALDH1A1 (0.39) | — | |
| SCHEMBL27189368 | 0.69 | ALDH1A1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL1938635 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 589 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8541569-B2 | Phosphoramidites for synthetic RNA in the reverse direction, efficient RNA synthesis and convenient introduction of 3'-end ligands, chromophores and modifications of synthetic RNA | CHEMGENES CORPORATION (US) | 2013-09-24 | — | — | US | claimed |
| EP-2560982-A2 | PHOSPHORAMIDITES FOR SYNTHETIC RNA IN THE REVERSE DIRECTION | Chemgenes Corporation (US) | 2013-02-27 | — | — | EP | claimed |
| US-20120149888-A1 | SYNTHESIS OF ARA-2'-O-METHYL-NUCLEOSIDES, CORRESPONDING PHOSPHORAMIDITES AND OLIGONUCLEOTIDES INCORPORATING NOVEL MODIFICATIONS FOR BIOLOGICAL APPLICATION IN THERAPEUCTICS, DIAGNOSTICS, G- TETRAD FORMING OLIGONUCLEOTIDES AND APTAMERS | CHEMGENES CORPORATION | 2012-06-14 | — | — | US | claimed |
| EP-2398815-A2 | SYNTHESIS OF ARA-2'-O-METHYL-NUCLEOSIDES, CORRESPONDING PHOSPHORAMIDITES AND OLIGONUCLEOTIDES INCORPORATING NOVEL MODIFICATIONS FOR BIOLOGICAL APPLICATION IN THERAPEUTICS, DIAGNOSTICS, G- TETRAD FORMING OLIGONUCLEOTIDES AND APTAMERS | Chemgenes Corporation (US) | 2011-12-28 | — | — | EP | claimed |
| WO-2011103468-A2 | PHOSPHORAMIDITES FOR SYNTHETIC RNA IN THE REVERSE DIRECTION | CHEMGENES CORPORATION (US) | 2011-08-25 | — | — | WO | claimed |
| US-20110137010-A1 | PHOSPHORAMIDITES FOR SYNTHETIC RNA IN THE REVERSE DIRECTION, EFFICIENT RNA SYNTHESIS AND CONVENIENT INTRODUCTION OF 3'-END LIGANDS, CHROMOPHORES AND MODIFICATIONS OF SYNTHETIC RNA | CHEMGENES CORPORATION (US) | 2011-06-09 | — | — | US | claimed |
| WO-2010096201-A2 | SYNTHESIS OF ARA-2'-O-METHYL-NUCLEOSIDES, CORRESPONDING PHOSPHORAMIDITES AND OLIGONUCLEOTIDES INCORPORATING NOVEL MODIFICATIONS FOR BIOLOGICAL APPLICATION IN THERAPEUTICS, DIAGNOSTICS, G- TETRAD FORMING OLIGONUCLEOTIDES AND APTAMERS | CHEMGENES CORPORATION (US) | 2010-08-26 | — | — | WO | claimed |
| CN-117126136-B | PARP7 inhibitor and application thereof | 安润医药科技（苏州）有限公司 | 2026-05-19 | — | — | CN | disclosed |
| WO-2026099473-A1 | OLIGONUCLEOTIDES WITH NEW INTERNUCLEOSIDE LINKAGE | VICO THERAPEUTICS B.V. (NL) | 2026-05-15 | — | — | WO | disclosed |
| US-20240391945-A1 | NUCLEIC ACID SYNTHESIS METHOD USING SEGMENT-TYPE AMIDITE | NITTO DENKO CORPORATION (JP) | 2024-11-28 | — | — | US | disclosed |
| WO-2024173343-A1 | COMPOUNDS TARGETING HYDROXYSTEROID 17-BETA DEHYDROGENASE (HSD17B) AND USES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2024-08-22 | — | — | WO | disclosed |
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |
| WO-2024107746-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES (US) | 2024-05-23 | — | — | WO | disclosed |
| EP-1317466-A2 | SYNTHONS FOR OLIGONUCLEOTIDE SYNTHESIS | Avecia Biotechnology, Inc. (US) | 2003-06-11 | — | — | EP | disclosed |
| EP-1294736-A1 | DEPROTECTION OF SYNTHETIC OLIGONUCLEOTIDES USING AN ACRYLONITRILE SCAVENGER | Avecia Biotechnology, Inc. (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2003004512-A1 | ACTIVATORS FOR OLIGONUCLEOTIDE SYNTHESIS | AVECIA BIOTECHNOLOGY INC. (US) | 2003-01-16 | — | — | WO | disclosed |
| US-20020072593-A1 | Method of preventing modification of synthetic oligonucleotides | AVECIA BIOTECHNOLOGY INC. | 2002-06-13 | — | — | US | disclosed |
| WO-2002020543-A2 | SYNTHONS FOR OLIGONUCLEOTIDE SYNTHESIS | AVECIA BIOTECHNOLOGY INC. (US) | 2002-03-14 | — | — | WO | disclosed |
| WO-2001096358-A1 | DEPROTECTION OF SYNTHETIC OLIGONUCLEOTIDES USING ACRYLONITRILE SCAVENGER | AVECIA BIOTECHNOLOGY, INC. (US) | 2001-12-20 | — | — | WO | disclosed |
| CN-1098718-A | Heterogeneous ring compound | ZENECA LTD (GB) | 1995-02-15 | — | — | CN | disclosed |