Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 3/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.37 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.37 |
| ▸ | USP14 | P54578 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | PMM2 | O15305 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4570434 | 0.91 | L3MBTL1 (0.64) | KDM4EATML3MBTL1ALDH1A1MEN1 | |
| SCHEMBL29385 | 0.89 | KDM4E (0.67) | KDM4EATML3MBTL1ALDH1A1METAP2 | |
| SCHEMBL29342487 | 0.87 | KDM4E (0.65) | KDM4EATML3MBTL1ALDH1A1MEN1 | |
| SCHEMBL20902507 | 0.82 | KDM4E (0.53) | KDM4EATML3MBTL1ALDH1A1MEN1 | |
| SCHEMBL23056709 | 0.82 | KDM4E (0.53) | KDM4EATML3MBTL1ALDH1A1RAB9A | |
| SCHEMBL29379 | 0.80 | ATM (0.55) | KDM4EATML3MBTL1ALDH1A1METAP2 | |
| SCHEMBL7605400 | 0.79 | KDM4E (0.53) | KDM4EATML3MBTL1ALDH1A1METAP2 | |
| SCHEMBL13589233 | 0.79 | KDM4E (0.53) | KDM4EATML3MBTL1ALDH1A1METAP2 | |
| SCHEMBL31397606 | 0.78 | L3MBTL1 (0.84) | KDM4EATML3MBTL1ALDH1A1MEN1 | |
| SCHEMBL77361 | 0.78 | L3MBTL1 (0.84) | KDM4EATML3MBTL1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3943492-A1 | TADF MATERIALS COMPRISING 4-(3-(2-(10H-PHENOXAZIN-10-YL)PYRIDIN-5-YL)-9H-CARBAZOL-9-YL)BENZONITRILE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN OLEDS | Noctiluca S.A. (PL) | 2022-01-26 | — | — | EP | disclosed |