Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.68 |
| ▸ | FABP3 | P05413 | 2/20 | 0.68 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.68 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 2/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL86091 | 0.82 | FABP4 (1.00) | FABP4FABP3FABP5NR3C1GAA | |
| SCHEMBL1069046 | 0.82 | FABP4 (0.64) | FABP4FABP3FABP5NR3C1GAA | |
| SCHEMBL14369263 | 0.81 | FABP4 (0.77) | FABP4FABP3FABP5NR3C1GAA | |
| SCHEMBL28654070 | 0.81 | FABP4 (0.96) | FABP4FABP3FABP5NR3C1GAA | |
| SCHEMBL28511172 | 0.81 | FABP4 (0.96) | FABP4FABP3FABP5NR3C1GAA | |
| SCHEMBL2322601 | 0.81 | FABP4 (0.96) | FABP4FABP3FABP5NR3C1GAA | |
| Ammonia Solution, Strong SCHEMBL17985319 | 0.81 | FABP4 (0.96) | FABP4FABP3FABP5NR3C1GAA | |
| Hydrochloric Acid SCHEMBL6374692 | 0.81 | FABP4 (0.96) | FABP4FABP3FABP5NR3C1GAA | |
| SCHEMBL12162268 | 0.79 | FABP4 (0.85) | FABP4FABP3FABP5NR3C1GAA | |
| Tetramethylammonium Ion SCHEMBL592343 | 0.77 | FABP4 (0.89) | FABP4FABP3FABP5NR3C1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11229624-B2 | FABP4 as a therapeutic target in skin diseases | TICURE LTD. (IL) | 2022-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11229624-B2 | FABP4 as a therapeutic target in skin diseases | FABP4, FABP2, FABP1 | FABP4 1/4885FABP3 5/4885FABP5 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.