Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24222000 | 0.84 | PDE4B (0.43) | PDE4BMEN1KMT2ARAB9ACYP1A2 | |
| SCHEMBL21883243 | 0.84 | TDP1 (0.47) | PDE4BMEN1KMT2AALDH1A1NOX1 | |
| SCHEMBL24221907 | 0.84 | ALDH1A1 (0.44) | PDE4BMEN1KMT2ARAB9ATGM2 | |
| SCHEMBL24221853 | 0.78 | MEN1 (0.47) | MEN1KMT2ARAB9ATGM2ALDH1A1 | |
| SCHEMBL21883217 | 0.74 | FBP1 (0.47) | MEN1KMT2ACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL24221933 | 0.74 | KMT2A (0.46) | PDE4BMEN1KMT2ARAB9ACYP1A2 | |
| SCHEMBL24221901 | 0.71 | MAPT (0.46) | PDE4BMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL18604415 | 0.68 | ALDH1A1 (0.46) | MEN1KMT2ARAB9ACYP1A2CYP2C19 | |
| SCHEMBL21883137 | 0.68 | SMN1; SMN2 (0.49) | PDE4BMEN1KMT2ARAB9ACYP1A2 | |
| SCHEMBL21883142 | 0.68 | SMN1; SMN2 (0.49) | PDE4BMEN1KMT2ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220024877-A1 | COMPOUNDS WITH COPPER- OR ZINC-ACTIVATED TOXICITY AGAINST MICROBIAL INFECTION | THE UAB RESEARCH FOUNDATION | 2022-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220024877-A1 | COMPOUNDS WITH COPPER- OR ZINC-ACTIVATED TOXICITY AGAINST MICROBIAL INFECTION | SLC39A11, CNBP, SLC39A3 | PDE4B 4696/4885MEN1 1706/4885KMT2A 2961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.