Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.56 |
| ▸ | CPA1 | P15085 | 2/20 | 0.53 |
| ▸ | CPA2 | P48052 | 1/20 | 0.53 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.50 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8270039 | 0.86 | NAALAD2 (0.70) | NAALAD2CPA1FOLH1MMP1MMP2 | |
| SCHEMBL22315435 | 0.84 | FOLH1 (0.60) | NAALAD2FOLH1 | |
| SCHEMBL22315882 | 0.84 | FOLH1 (0.60) | NAALAD2FOLH1 | |
| SCHEMBL22316576 | 0.84 | FOLH1 (0.60) | NAALAD2FOLH1 | |
| SCHEMBL14554015 | 0.84 | NAALAD2 (0.62) | NAALAD2FOLH1MMP1MMP8MME | |
| SCHEMBL22316165 | 0.83 | FOLH1 (0.62) | NAALAD2FOLH1 | |
| SCHEMBL20431098 | 0.83 | ALDH1A1 (0.48) | CPA1MMP1MMP3MMP2MMP12 | |
| SCHEMBL14552676 | 0.83 | NAALAD2 (0.61) | NAALAD2FOLH1MMP1MMP8MME | |
| SCHEMBL12683553 | 0.81 | MME (0.58) | CPA1MMEACEACE2 | |
| SCHEMBL164831 | 0.81 | MME (0.58) | CPA1MMEACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11229614-B2 | Supramolecular hydrogel applications to the carotid bodies to treat hypertension and sleep apnea in obesity | THE JOHNS HOPKINS UNIVERSITY (US) | 2022-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11229614-B2 | Supramolecular hydrogel applications to the carotid bodies to treat hypertension and sleep apnea in obesity | TRPM7, TRPC7, TRPM4 | NAALAD2 3142/4885CPA1 1446/4885CPA2 1517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.