Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CDC25A | P30304 | 1/20 | 0.31 |
| ▸ | CDC25C | P30307 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2430119 | 0.74 | ALDH1A1 (0.49) | POLBALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL12324684 | 0.70 | POLB (0.42) | POLBRAB9AALDH1A1NPC1MAPT | |
| SCHEMBL2429164 | 0.70 | CYP2C9 (0.46) | RAB9AALDH1A1NPC1MAPTKMT2A | |
| SCHEMBL8175559 | 0.67 | ALDH1A1 (0.55) | POLBRAB9AALDH1A1NPC1MAPT | |
| SCHEMBL31124704 | 0.67 | ALDH1A1 (0.55) | POLBRAB9AALDH1A1NPC1MAPT | |
| SCHEMBL2425388 | 0.66 | MAPT (0.48) | POLBRAB9AALDH1A1NPC1MAPT | |
| SCHEMBL2424187 | 0.63 | MAOA (0.43) | ALDH1A1MAPTKMT2AHPGDKDM4E | |
| SCHEMBL2428346 | 0.63 | ESR2 (0.43) | ALDH1A1HPGDKDM4ESMN1; SMN2GAA | |
| SCHEMBL13910970 | 0.63 | POLB (0.64) | POLBRAB9AALDH1A1NPC1MAPT | |
| SCHEMBL2420589 | 0.63 | CA12 (0.50) | POLBRAB9AALDH1A1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2368895-A1 | Ferrocenyl flavonoids | Centre National de la Recherche Scientifique (CNRS) (FR) | 2011-09-28 | — | — | EP | disclosed |