SCHEMBL2422372

SCHEMBL2422372

CCOC(=O)C(Br)(c1ccccc1)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 2/20 0.54
ALDH1A1 P00352 2/20 0.47
RECQL P46063 1/20 0.47
MMP8 P22894 1/20 0.47
TSHR P16473 2/20 0.47
POLB P06746 3/20 0.46
NPSR1 Q6W5P4 1/20 0.46
KCNN4 O15554 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
KMT2A Q03164 5/20 0.44
MEN1 O00255 4/20 0.44
CHRM2 P08172 2/20 0.44
CHRM1 P11229 2/20 0.44
CHRM3 P20309 2/20 0.44
CHRM4 P08173 1/20 0.44
CHRM5 P08912 1/20 0.44
MAPT P10636 1/20 0.44
THRB P10828 1/20 0.44
GAA P10253 1/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7646732 0.85 PIN1 (0.54) PIN1ALDH1A1RECQLMMP8TSHR
SCHEMBL2420371 0.85 PIN1 (0.54) PIN1ALDH1A1RECQLMMP8TSHR
SCHEMBL9725190 0.83 PIN1 (0.53) PIN1ALDH1A1RECQLMMP8TSHR
SCHEMBL9254249 0.83 PIN1 (0.53) PIN1ALDH1A1RECQLMMP8TSHR
SCHEMBL5639395 0.82 PIN1 (0.56) PIN1ALDH1A1RECQLMMP8TSHR
SCHEMBL1647761 0.82 KCNN4 (0.62) PIN1ALDH1A1RECQLMMP8TSHR
SCHEMBL2418304 0.82 TSHR (0.53) ALDH1A1TSHRPOLBNPSR1KMT2A
SCHEMBL2393258 0.81 PIN1 (0.51) PIN1ALDH1A1RECQLMMP8TSHR
SCHEMBL395978 0.81 PIN1 (0.54) PIN1ALDH1A1RECQLMMP8TSHR
SCHEMBL2910521 0.81 PIN1 (0.54) PIN1ALDH1A1RECQLMMP8TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8278404-B2 Process for producing copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-02 US disclosed
US-20110224390-A1 PROCESS FOR PRODUCING COPOLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-09-15 US disclosed
US-7262258-B2 Process for producing copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-08-28 US disclosed
US-20070088139-A1 PROCESS FOR PRODUCING COPOLYMER SUMITOMO CHEMICAL COMPANY, LIMITED 2007-04-19 US disclosed
US-20050014914-A1 Process for producing copolymer SUMITOMO CHEMICAL COMPANY, LIMITED 2005-01-20 US disclosed
CN-1042639-C Process for the preparation of low molecular weight copolymers of ethylene and at least one other 1-olefin DSM NV (NL) 1999-03-24 CN disclosed
US-5728911-A CATALYTIC SOLUTION COPOLYMERIZATION OF ETHYLENE WITH POLYUNSATURATED MONOMER DSM COPOLYMER, INC. (US) 1998-03-17 US disclosed
EP-0705284-B1 PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE DSM NV (NL) 1997-07-09 EP disclosed
CN-1125954-A Process for the preparation of low molecular weight copolymers of ethylene and at least one other 1-olefin DSM NV (NL) 1996-07-03 CN disclosed
EP-0705284-A1 PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE DSM NV (NL) 1996-04-10 EP disclosed
WO-1995000564-A1 PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE DSM N.V. (NL) 1995-01-05 WO disclosed
EP-0045165-B1 RHODANINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION, AND ALDOSE REDUCTASE INHIBITORS CONTAINING SUCH DERIVATIVES ONO PHARMACEUTICAL CO., LTD. (JP) 1986-03-12 EP disclosed
EP-0044119-B1 PROCESS FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE STAMICARBON B.V. (NL) 1985-05-29 EP disclosed
US-4446143-A Rhodanine derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1984-05-01 US disclosed
US-4435552-A COORDINATION CATALYST CONTAINING HALOACYL COMPOUND STAMICARBON B.V. (NL) 1984-03-06 US disclosed
EP-0045165-A1 Rhodanine derivatives, a process for their preparation, and aldose reductase inhibitors containing such derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1982-02-03 EP disclosed
EP-0044119-A2 Process for the preparation of copolymers of ethylene with at least one other 1-alkene STAMICARBON B.V. (NL) 1982-01-20 EP disclosed