Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2422372 | 0.83 | PIN1 (0.54) | PIN1ALDH1A1RECQLMMP8TSHR | |
| SCHEMBL7646732 | 0.83 | PIN1 (0.54) | PIN1ALDH1A1RECQLMMP8TSHR | |
| SCHEMBL2420371 | 0.83 | PIN1 (0.54) | PIN1ALDH1A1RECQLMMP8TSHR | |
| SCHEMBL21659699 | 0.83 | KCNN4 (0.60) | ALDH1A1TSHRPOLBCHRM2CHRM1 | |
| SCHEMBL28970082 | 0.81 | CHRM2 (0.65) | PIN1ALDH1A1RECQLMMP8TSHR | |
| SCHEMBL9725190 | 0.81 | PIN1 (0.53) | PIN1ALDH1A1RECQLMMP8TSHR | |
| SCHEMBL5474434 | 0.81 | PIN1 (0.53) | PIN1ALDH1A1RECQLMMP8TSHR | |
| SCHEMBL8483586 | 0.81 | PIN1 (0.53) | PIN1ALDH1A1RECQLMMP8TSHR | |
| SCHEMBL10745657 | 0.81 | PIN1 (0.53) | PIN1ALDH1A1RECQLMMP8TSHR | |
| SCHEMBL5639395 | 0.81 | PIN1 (0.56) | PIN1ALDH1A1RECQLMMP8TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119591509-A | Synthesis method of trimebutine intermediate and trimebutine maleate | 五峰赤诚生物科技股份有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-119591509-A | Synthesis method of trimebutine intermediate and trimebutine maleate | 五峰赤诚生物科技股份有限公司 | 2025-03-11 | — | — | CN | disclosed |
| US-5401766-A | Hypotensive agents with vasodilation | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-28 | — | — | US | disclosed |
| US-5162362-A | Hypotensive agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-10 | — | — | US | disclosed |
| US-5158959-A | Treatment of hypertension | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-27 | — | — | US | disclosed |