Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 7/20 | 0.71 |
| ▸ | CTSS | P25774 | 3/20 | 0.64 |
| ▸ | CTSK | P43235 | 2/20 | 0.64 |
| ▸ | CTSL | P07711 | 1/20 | 0.64 |
| ▸ | CTSB | P07858 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | ACE | P12821 | 1/20 | 0.61 |
| ▸ | MME | P08473 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498474 | 1.00 | REN (0.71) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL28611118 | 1.00 | REN (0.71) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL12242944 | 1.00 | REN (0.71) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL18229266 | 1.00 | REN (0.71) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL7269523 | 1.00 | REN (0.71) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL9551232 | 0.99 | REN (0.73) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL5994686 | 0.96 | REN (0.73) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL9101385 | 0.96 | REN (0.73) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL6897460 | 0.96 | REN (0.73) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL3046634 | 0.96 | REN (0.73) | RENCTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220024949-A1 | CU-AND NI-CATALYZED DECARBOXYLATIVE BORYLATION REACTIONS | THE SCRIPPS RESEARCH INSTITUTE | 2022-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220024949-A1 | CU-AND NI-CATALYZED DECARBOXYLATIVE BORYLATION REACTIONS | PCSK9, PCSK7, PCSK6 | REN 100/4885CTSS 309/4885CTSK 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.