Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 2/20 | 0.58 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPK3 | P27361 | 6/20 | 0.48 |
| ▸ | BMX | P51813 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.44 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21264082 | 0.86 | BTK (0.46) | TGM2MAPK3MEN1KMT2AHTT | |
| SCHEMBL17524754 | 0.84 | TGM2 (0.56) | TGM2KDM4EMAPK3BMXMEN1 | |
| SCHEMBL11055173 | 0.82 | TAS2R14 (0.60) | TAS2R14KDM4EMEN1KMT2AGAA | |
| SCHEMBL15938701 | 0.82 | TGM2 (0.58) | TGM2KDM4EMAPK3MEN1KMT2A | |
| SCHEMBL5166111 | 0.81 | CYP1A2 (0.60) | TAS2R14MEN1KMT2AGAABRAF | |
| SCHEMBL28549394 | 0.80 | CFTR (0.56) | TGM2KDM4EMAPK3MEN1KMT2A | |
| SCHEMBL18897398 | 0.80 | TGM2 (0.52) | TGM2KDM4EMAPK3MEN1KMT2A | |
| SCHEMBL28141674 | 0.80 | TAS2R14 (0.57) | TAS2R14KDM4EMEN1KMT2AGAA | |
| SCHEMBL21894170 | 0.79 | TGM2 (0.58) | TGM2MAPK3MEN1KMT2AGAA | |
| SCHEMBL31162390 | 0.79 | TGM2 (0.58) | TGM2MAPK3MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3943087-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | Celgene CAR LLC (BM) | 2022-01-26 | — | — | EP | disclosed |