Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 1.00 |
| ▸ | TP53 | P04637 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 3/20 | 1.00 |
| ▸ | NPC1 | O15118 | 3/20 | 1.00 |
| ▸ | RAB9A | P51151 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 3/20 | 1.00 |
| ▸ | THPO | P40225 | 3/20 | 1.00 |
| ▸ | GMNN | O75496 | 3/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 3/20 | 1.00 |
| ▸ | MTOR | P42345 | 2/20 | 1.00 |
| ▸ | BLM | P54132 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | STAT6 | P42226 | 1/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TFPI2 | P48307 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cantharidic_Acid SCHEMBL943636 | 1.00 | MAPK1 (1.00) | MAPK1TP53LMNAHIF1ANPC1 | |
| Cantharidic_Acid SCHEMBL13091537 | 1.00 | MAPK1 (1.00) | MAPK1TP53LMNAHIF1ANPC1 | |
| SCHEMBL16542813 | 0.91 | MAPK1 (0.83) | MAPK1TP53LMNAHIF1ANPC1 | |
| SCHEMBL3494225 | 0.88 | MAPK1 (0.77) | MAPK1TP53LMNAHIF1ANPC1 | |
| SCHEMBL20885049 | 0.83 | MAPK1 (0.70) | MAPK1TP53LMNAHIF1ANPC1 | |
| SCHEMBL14398404 | 0.82 | MAPK1 (0.67) | MAPK1TP53LMNAHIF1ANPC1 | |
| SCHEMBL27616131 | 0.78 | MAPK1 (0.61) | MAPK1TP53LMNAHIF1ANPC1 | |
| SCHEMBL20885003 | 0.76 | MAPK1 (0.59) | MAPK1TP53LMNAHIF1ANPC1 | |
| Cantharidic_Acid SCHEMBL29360065 | 0.76 | MAPK1 (0.61) | MAPK1TP53LMNAHIF1ANPC1 | |
| SCHEMBL28493026 | 0.69 | MAPK1 (0.52) | MAPK1TP53LMNAHIF1ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220024943-A1 | HIGH PURITY CANTHARIDIN MANUFACTURING PROCESS AND COMPOSITIONS | SOL-GEL TECHNOLOGIES LTD. (IL) | 2022-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220024943-A1 | HIGH PURITY CANTHARIDIN MANUFACTURING PROCESS AND COMPOSITIONS | CUTA, TYR, VNN1 | MAPK1 2614/4885TP53 3739/4885LMNA 4114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.