Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 16/20 | 0.45 |
| ▸ | EZH1 | Q92800 | 7/20 | 0.43 |
| ▸ | EED | O75530 | 5/20 | 0.43 |
| ▸ | SUZ12 | Q15022 | 5/20 | 0.43 |
| ▸ | RBBP4 | Q09028 | 4/20 | 0.43 |
| ▸ | AEBP2 | Q6ZN18 | 4/20 | 0.43 |
| ▸ | RBBP7 | Q16576 | 2/20 | 0.43 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.41 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.41 |
| ▸ | PDE9A | O76083 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17734418 | 0.87 | EZH2 (0.56) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL23863703 | 0.81 | EZH2 (0.52) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL17734413 | 0.74 | EZH2 (0.71) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL23863707 | 0.73 | EZH2 (0.33) | EZH2EZH1PDE9A | |
| SCHEMBL23863704 | 0.72 | PDE9A (0.46) | EZH2EEDSUZ12PDE9A | |
| SCHEMBL17734416 | 0.72 | EZH2 (0.44) | EZH2EZH1EEDSUZ12PDE9A | |
| SCHEMBL20612508 | 0.71 | EZH2 (0.77) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL19503276 | 0.71 | EZH2 (0.57) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL19503275 | 0.70 | EZH2 (0.55) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL21914671 | 0.70 | EZH2 (0.65) | EZH2EZH1EEDSUZ12RBBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11236082-B2 | EZH2 inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11236082-B2 | EZH2 inhibitors and uses thereof | EZH2, EZH1, BMI1 | EZH2 1/4885EZH1 2/4885EED 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.