Diphenamide

Diphenamide

SCHEMBL2422747

C#N.C#N.CN(C)C(=O)C(c1ccccc1)c1ccccc1.CN(C)C(=O)C(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.50
ATM Q13315 1/20 0.50
ALDH1A1 P00352 1/20 0.50
TDP1 Q9NUW8 2/20 0.49
OPRM1 P35372 1/20 0.49
OPRL1 P41146 1/20 0.49
TACR1 P25103 3/20 0.47
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
CRHBP P24387 1/20 0.46
CRHR2 Q13324 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenamide SCHEMBL12501720 0.94 ALDH1A1 (0.56) KDM4EATMALDH1A1TDP1OPRM1
Diphenamide SCHEMBL9202269 0.94 ALDH1A1 (0.55) KDM4EATMALDH1A1TDP1OPRM1
Diphenamide SCHEMBL6910614 0.94 ALDH1A1 (0.55) KDM4EATMALDH1A1TDP1OPRM1
Diphenamide SCHEMBL39339 0.94 ALDH1A1 (0.55) KDM4EATMALDH1A1TDP1OPRM1
Diphenamide SCHEMBL23534079 0.92 ALDH1A1 (0.53) KDM4EATMALDH1A1TDP1OPRM1
Diphenamide SCHEMBL10338756 0.92 ALDH1A1 (0.53) KDM4EATMALDH1A1TDP1OPRM1
Diphenamide SCHEMBL2051916 0.92 ALDH1A1 (0.53) KDM4EATMALDH1A1TDP1OPRM1
Diphenamide SCHEMBL22345014 0.92 ALDH1A1 (0.53) KDM4EATMALDH1A1TDP1OPRM1
Diphenamide SCHEMBL11211674 0.92 ALDH1A1 (0.53) KDM4EATMALDH1A1TDP1OPRM1
Diphenamide SCHEMBL12477138 0.92 ALDH1A1 (0.53) KDM4EATMALDH1A1TDP1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62128165-A None JP disclosed
JP-5129347-A None JP disclosed
US-10113111-B2 Treated fillers and uses thereof DOW SILICONES CORPORATION (US) 2018-10-30 US disclosed
EP-2607413-B1 Plastic Substrate for Automotive Glazing and Its Repairing Method SHINETSU CHEMICAL CO (JP) 2017-06-21 EP disclosed
WO-2016126326-A1 TREATED FILLERS AND USES THEREOF DOW CORNING CORPORATION (US) 2016-08-11 WO disclosed
US-20160230084-A1 Treated Fillers And Uses Thereof DOW SILICONES CORPORATION 2016-08-11 US disclosed
US-20130164539-A1 PLASTIC SUBSTRATE FOR AUTOMOTIVE GLAZING AND ITS REPAIRING METHOD KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2013-06-27 US disclosed
EP-2607413-A1 Plastic Substrate for Automotive Glazing and Its Repairing Method Shin-Etsu Chemical Co., Ltd. (JP) 2013-06-26 EP disclosed
US-8198544-B2 Printed wiring board and manufacturing method thereof IBIDEN CO., LTD. (JP) 2012-06-12 US disclosed
EP-1835790-B1 PRINTED WIRING BOARD IBIDEN CO LTD (JP) 2011-11-02 EP disclosed
US-8013057-B2 White thermosetting silicone resin composition for molding an optical semiconductor case and optical semiconductor case SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-09-06 US disclosed
US-20100252308-A1 PRINTED WIRING BOARD AND MANUFACTURING METHOD THEREOF IBIDEN CO., LTD. (JP) 2010-10-07 US disclosed
US-7804031-B2 Printed wiring board and manufacturing method thereof IBIDEN CO., LTD. (JP) 2010-09-28 US disclosed
US-20090239997-A1 WHITE THERMOSETTING SILICONE RESIN COMPOSITION FOR MOLDING AN OPTICAL SEMICONDUCTOR CASE AND OPTICAL SEMICONDUCTOR CASE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-09-24 US disclosed
US-20070273047-A1 PRINTED WIRING BOARD AND MANUFACTURING METHOD THEREOF IBIDEN CO., LTD (JP) 2007-11-29 US disclosed
EP-1835790-A1 PRINTED WIRING BOARD IBIDEN CO., LTD. (JP) 2007-09-19 EP disclosed
JP-H05129347-A BONDING AGENT FOR SEMICONDUCTOR ELEMENT AND SEMICONDUCTOR DEVICE HITACHI CHEM CO LTD 1993-05-25 JP disclosed
JP-S62128165-A SUNSTRATE FOR MODULE HITACHI LTD 1987-06-10 JP disclosed