Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16090628 | 0.89 | PIK3CD (0.37) | CASP3PIK3CDJAK2JAK1TYK2 | |
| SCHEMBL3927362 | 0.87 | CASP3 (0.36) | CASP3PIK3CDJAK2JAK1TYK2 | |
| SCHEMBL3089108 | 0.80 | CA1 (0.30) | CA1 | |
| SCHEMBL2610343 | 0.80 | CA1 (0.42) | CA1 | |
| SCHEMBL23868103 | 0.74 | TDP1 (0.32) | — | |
| SCHEMBL10090160 | 0.73 | MEN1 (0.43) | CASP3PIK3CDGSTO1 | |
| SCHEMBL5266553 | 0.72 | CA1 (0.32) | CA1 | |
| SCHEMBL13585042 | 0.72 | PMP22 (0.45) | — | |
| SCHEMBL15216239 | 0.72 | TSHR (0.50) | — | |
| SCHEMBL3049834 | 0.71 | PIK3CD (0.37) | CASP3PIK3CDGSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233813-B1 | PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS | GEISTLICH PHARMA AG (CH) | 2022-02-02 | — | — | EP | disclosed |