Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.39 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.35 |
| ▸ | FNTB | P49356 | 2/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | GRN | P28799 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GGH | Q92820 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8247958 | 0.81 | FOLH1 (0.38) | FOLH1NAALAD2RIMKLAFNTAFNTB | |
| SCHEMBL27369474 | 0.77 | NOD1 (0.38) | FOLH1NAALAD2RIMKLANOD1GRN | |
| SCHEMBL24693135 | 0.74 | FOLH1 (0.40) | FOLH1NAALAD2RIMKLAFNTAFNTB | |
| SCHEMBL26439972 | 0.74 | FOLH1 (0.40) | FOLH1NAALAD2RIMKLAFNTAFNTB | |
| SCHEMBL6121310 | 0.73 | PPARA (0.48) | FOLH1 | |
| SCHEMBL2433802 | 0.73 | PPARA (0.48) | FOLH1 | |
| SCHEMBL12436316 | 0.73 | PPARA (0.48) | FOLH1 | |
| SCHEMBL14557466 | 0.73 | MAPT (0.57) | FOLH1NAALAD2RIMKLAFNTAFNTB | |
| SCHEMBL11885251 | 0.73 | MAPT (0.57) | FOLH1NAALAD2RIMKLAFNTAFNTB | |
| SCHEMBL26298441 | 0.71 | FOLH1 (0.40) | FOLH1NAALAD2RIMKLANOD1GRN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022026631-A1 | CONJUGATED HEPCIDIN MIMETICS | PROTAGONIST THERAPEUTICS, INC. (US) | 2022-02-03 | — | — | WO | disclosed |
| WO-2022026629-A1 | CONJUGATED HEPCIDIN MIMETICS | PROTAGONIST THERAPEUTICS, INC. (US) | 2022-02-03 | — | — | WO | disclosed |