Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.40 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.40 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 2/20 | 0.35 |
| ▸ | FNTB | P49356 | 2/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | GRN | P28799 | 2/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22271607 | 0.84 | FPR2 (0.39) | FOLH1NAALAD2RIMKLAACACBACACA | |
| SCHEMBL22271602 | 0.84 | FPR2 (0.39) | FOLH1NAALAD2RIMKLAACACBACACA | |
| SCHEMBL20013297 | 0.83 | ACACB (0.38) | FOLH1NAALAD2RIMKLAACACBACACA | |
| SCHEMBL26439972 | 0.78 | FOLH1 (0.40) | FOLH1NAALAD2RIMKLAFNTAFNTB | |
| SCHEMBL12436316 | 0.74 | PPARA (0.48) | FOLH1 | |
| SCHEMBL6121310 | 0.74 | PPARA (0.48) | FOLH1 | |
| SCHEMBL2433802 | 0.74 | PPARA (0.48) | FOLH1 | |
| SCHEMBL24230568 | 0.74 | FOLH1 (0.39) | FOLH1NAALAD2RIMKLAFNTAFNTB | |
| SCHEMBL14557466 | 0.74 | MAPT (0.57) | FOLH1NAALAD2RIMKLAFNTAFNTB | |
| SCHEMBL11885251 | 0.74 | MAPT (0.57) | FOLH1NAALAD2RIMKLAFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253202-A1 | POLYPEPTIDE DERIVATIVE HAVING EFFECT OF DUAL TARGETED ACTIVATION OF GLP-1R AND GIPR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 南京知和医药科技有限公司 | 2022-12-08 | — | — | WO | disclosed |