SCHEMBL2423163

SCHEMBL2423163

C1=CC=CNC=C1.c1ccc2c(-c3cccc4ccccc34)cccc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.43
▸ ALPL P05186 1/20 0.43
▸ GAA P10253 1/20 0.43
▸ NISCH Q9Y2I1 1/20 0.42
▸ CA12 O43570 1/20 0.41
▸ CA1 P00915 1/20 0.41
▸ CA2 P00918 1/20 0.41
▸ CA9 Q16790 1/20 0.41
▸ ALDH1A1 P00352 3/20 0.40
▸ CYP2A6 P11509 3/20 0.40
▸ TSHR P16473 2/20 0.40
▸ HSD17B10 Q99714 2/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ PTPN1 P18031 1/20 0.39
▸ TYMP P19971 1/20 0.39
▸ GSK3B P49841 2/20 0.38
▸ PI4KA P42356 1/20 0.38
▸ PI4K2B Q8TCG2 1/20 0.38
▸ PI4K2A Q9BTU6 1/20 0.38
▸ PI4KB Q9UBF8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27739439 0.90 CA12 (0.49) KDM4EALPLGAANISCHCA12
Hydrochloric Acid SCHEMBL27851161 0.88 CA12 (0.47) KDM4EALPLGAANISCHCA12
Hydrochloric Acid SCHEMBL28800693 0.88 CA12 (0.47) KDM4EALPLGAANISCHCA12
Phenanthrene SCHEMBL27586708 0.84 ALDH1A1 (0.60) ALDH1A1CYP2A6TSHRHSD17B10TDP1
Phenanthrene SCHEMBL28869286 0.84 ALDH1A1 (0.60) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL25302086 0.81 ALDH1A1 (0.59) KDM4EALPLGAANISCHCA12
SCHEMBL27953 0.81 ALDH1A1 (0.59) KDM4EALPLGAANISCHCA12
SCHEMBL29350007 0.81 ALDH1A1 (0.59) KDM4EALPLGAANISCHCA12
Hydrochloric Acid SCHEMBL4268575 0.78 ALDH1A1 (0.56) KDM4EALPLGAANISCHALDH1A1
SCHEMBL18174178 0.78 ALDH1A1 (0.56) KDM4EALPLGAANISCHCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2547675-B1 PROCESS FOR PREPARING DIVINYLARENE DIOXIDES DOW GLOBAL TECHNOLOGIES LLC (US) 2014-01-22 — — EP claimed
US-20130041165-A1 PROCESS FOR PREPARING DIVINYLARENE DIOXIDES GULYAS GYONGYI (US) 2013-02-14 — — US claimed
EP-2547669-A1 PROCESS FOR PREPARING DIVINYLARENE DIOXIDES Dow Global Technologies LLC (US) 2013-01-23 — — EP claimed
EP-2547675-A2 PROCESS FOR PREPARING DIVINYLARENE DIOXIDES Dow Global Technologies LLC (US) 2013-01-23 — — EP claimed
US-20130005998-A1 PROCESS FOR PREPARING DIVINYLARENE DIOXIDES BLUE CUBE IP LLC 2013-01-03 — — US claimed
WO-2011116180-A1 PROCESS FOR PREPARING DIVINYLARENE DIOXIDES DOW GLOBAL TECHNOLOGIES LLC (US) 2011-09-22 — — WO claimed
WO-2011116177-A2 PROCESS FOR PREPARING DIVINYLARENE DIOXIDES DOW GLOBAL TECHNOLOGIES (US) 2011-09-22 — — WO claimed
EP-2547675-B1 PROCESS FOR PREPARING DIVINYLARENE DIOXIDES DOW GLOBAL TECHNOLOGIES LLC (US) 2014-01-22 — — EP disclosed
US-20130041165-A1 PROCESS FOR PREPARING DIVINYLARENE DIOXIDES GULYAS GYONGYI (US) 2013-02-14 — — US disclosed
EP-2547669-A1 PROCESS FOR PREPARING DIVINYLARENE DIOXIDES Dow Global Technologies LLC (US) 2013-01-23 — — EP disclosed
US-20130005998-A1 PROCESS FOR PREPARING DIVINYLARENE DIOXIDES BLUE CUBE IP LLC 2013-01-03 — — US disclosed
WO-2011116180-A1 PROCESS FOR PREPARING DIVINYLARENE DIOXIDES DOW GLOBAL TECHNOLOGIES LLC (US) 2011-09-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130041165-A1 PROCESS FOR PREPARING DIVINYLARENE DIOXIDES SCO2, APEX1, SQLE KDM4E 1995/4885ALPL 3931/4885GAA 4421/4885
US-20130005998-A1 PROCESS FOR PREPARING DIVINYLARENE DIOXIDES DAO, DDO, SCO2 KDM4E 3089/4885ALPL 3171/4885GAA 1500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback