SCHEMBL27953

SCHEMBL27953

c1ccc2c(-c3cccc4ccccc34)cccc2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.59
HSD17B10 Q99714 7/20 0.59
TSHR P16473 5/20 0.59
CYP2A6 P11509 3/20 0.59
TDP1 Q9NUW8 2/20 0.59
HPRT1 P00492 1/20 0.53
HPGD P15428 4/20 0.52
CYP1A2 P05177 3/20 0.52
CYP3A4 P08684 1/20 0.52
KEAP1 Q14145 1/20 0.52
MAPK1 P28482 3/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
ATM Q13315 2/20 0.50
KDM4E B2RXH2 2/20 0.50
PTPN1 P18031 1/20 0.50
ALPL P05186 1/20 0.50
GAA P10253 1/20 0.50
NISCH Q9Y2I1 1/20 0.48
POLB P06746 1/20 0.48
HIF1A Q16665 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29350007 1.00 ALDH1A1 (0.59) ALDH1A1HSD17B10TSHRCYP2A6TDP1
SCHEMBL25302086 1.00 ALDH1A1 (0.59) ALDH1A1HSD17B10TSHRCYP2A6TDP1
Hydrochloric Acid SCHEMBL4268575 0.97 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRCYP2A6TDP1
SCHEMBL2638067 0.97 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRCYP2A6TDP1
Phosphine SCHEMBL6665557 0.97 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRCYP2A6TDP1
Ammonia Solution, Strong SCHEMBL3156160 0.97 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRCYP2A6TDP1
SCHEMBL6077039 0.97 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRCYP2A6TDP1
Bromide SCHEMBL7106161 0.97 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRCYP2A6TDP1
SCHEMBL17836548 0.97 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRCYP2A6TDP1
Bromide SCHEMBL8588309 0.97 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRCYP2A6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 17503 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4749337-A1 METHOD FOR PRODUCING CHOLESTERIC LIQUID CRYSTAL LAYER, CHOLESTERIC LIQUID CRYSTAL LAYER, REFLECTIVE FILM, LAMINATED GLASS, HEAD-UP DISPLAY SYSTEM, AND COMPOSITION FUJIFILM Corporation (JP) 2026-05-27 EP claimed
CN-122080405-A High-insulation binaphthyl polyimide dielectric film and preparation method and application thereof 2026-05-26 CN claimed
CN-122079895-A Process for preparing N, S-acetal compounds based on transition metal catalytic systems 2026-05-26 CN claimed
CN-122079806-A Method for preparing chiral benzhydrol compound by rhodium-catalyzed asymmetric hydrogenation of o-amidobenzophenone and application of chiral benzhydrol compound 2026-05-26 CN claimed
CN-122071417-A Method for preparing chiral amine compound by asymmetric hydrogenation of ruthenium catalytic imine 中国科学院大连化学物理研究所 2026-05-22 CN claimed
CN-122010689-A Preparation method of cycloparaffin 浙江清华长三角研究院 2026-05-12 CN claimed
US-12628556-B2 Plurality of host materials and organic electroluminescent device comprising the same DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2026-05-12 US claimed
US-20260110911-A1 METHOD FOR PRODUCING CHOLESTERIC LIQUID CRYSTAL LAYER, CHOLESTERIC LIQUID CRYSTAL LAYER, REFLECTIVE FILM, LAMINATED GLASS, HEAD-UP DISPLAY SYSTEM, AND COMPOSITION FUJIFILM CORPORATION (JP) 2026-04-23 US claimed
EP-3262055-B1 WATER SOLUBLE FLUORESCENT OR COLORED DYES COMPRISING CONJUGATING GROUPS SONY GROUP CORP (JP) 2026-04-22 EP claimed
US-12606566-B2 Substituted cyclopenta[4,5]pyrrolo[1,2-a]pyrazines as bruton's tyrosine kinase inhibitors SHANGHAI SYNERGY PHARMACEUTICAL SCIENCES CO., LTD. (CN) 2026-04-21 US claimed
EP-0170470-A2 Process for the preparation of optically active enamines or imines Takasago Perfumery Co., Ltd. (JP) 1986-02-05 EP claimed
US-4562280-A WITH CHLOROMETHYL ALKYL ETHER IN PRESENCE OF CATALYIC FERRIC OR STANNIC CHLORIDE THE DOW CHEMICAL COMPANY (US) 1985-12-31 US claimed
WO-1985005355-A1 A PROCESS FOR THE PREPARATION OF CYCLOBUTENE-SUBSTITUTED AROMATIC HYDROCARBONS THE DOW CHEMICAL COMPANY (US) 1985-12-05 WO claimed
US-4540763-A Polymers derived from poly(arylcyclobutenes) THE DOW CHEMICAL COMPANY (US) 1985-09-10 US claimed
EP-0147548-A2 Novel polyaromatic cyanates and polytriazines prepared therefrom THE DOW CHEMICAL COMPANY (US) 1985-07-10 EP claimed
US-4528366-A Production of polytriazines from aromatic polycyanates with cobalt salt of a carboxylic acid as catalyst THE DOW CHEMICAL COMPANY (US) 1985-07-09 US claimed
US-4281074-A Process of manufacturing cured unsaturated polyester resins with a regular network structure POLSKA AKADEMIA NAUK, ZAKLAD POLIMEROW (PL) 1981-07-28 US claimed
US-4113959-A METHOD FOR RESOLVING AMINO AND AMMONIUM COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1978-09-12 US claimed
US-4043979-A Polymer-multiheteromacrocycles THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1977-08-23 US claimed
US-3952052-A Process for producing alkali metal salts of aromatic polycarboxylic acids PHILLIPS PETROLEUM COMPANY (US) 1976-04-20 US claimed