⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29997540 | 0.91 | MMP13 (0.34) | — | |
| SCHEMBL13244929 | 0.86 | — | — | |
| SCHEMBL16843264 | 0.84 | — | — | |
| SCHEMBL13245141 | 0.84 | — | — | |
| SCHEMBL932293 | 0.83 | — | — | |
| SCHEMBL932292 | 0.83 | — | — | |
| SCHEMBL13245191 | 0.83 | — | — | |
| SCHEMBL13245610 | 0.83 | — | — | |
| SCHEMBL26798197 | 0.82 | MMP13 (0.33) | — | |
| Achn-975 SCHEMBL13737986 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827612-B2 | Hydroxamic acid derivative, method for producing same and use thereof | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2023-11-28 | — | — | US | disclosed |
| US-11827612-B2 | Hydroxamic acid derivative, method for producing same and use thereof | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2023-11-28 | — | — | US | disclosed |
| EP-4071134-A1 | HYDROXAMIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences (CN) | 2022-10-12 | — | — | EP | disclosed |
| US-20220033369-A1 | HYDROXAMIC ACID DERIVATIVE, METHOD FOR PRODUCING SAME AND USE THEREOF | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2022-02-03 | — | — | US | disclosed |