Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | FABP6 | P51161 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1800666 | 0.84 | HPGDS (0.63) | HPGDSALDH1A1HPGDPOLBRAB9A | |
| SCHEMBL1801541 | 0.82 | HPGDS (0.53) | HPGDSALDH1A1HPGDPOLBRAB9A | |
| SCHEMBL1799866 | 0.82 | HPGDS (0.61) | HPGDSALDH1A1HPGDPOLBRAB9A | |
| SCHEMBL1800987 | 0.81 | HPGDS (0.57) | HPGDSALDH1A1HPGDPOLBRAB9A | |
| SCHEMBL1802043 | 0.80 | HPGDS (0.59) | HPGDSALDH1A1HPGDPOLBRAB9A | |
| SCHEMBL1799020 | 0.80 | HPGDS (0.69) | HPGDSALDH1A1HPGDPOLBRAB9A | |
| SCHEMBL1799752 | 0.80 | HPGDS (0.61) | HPGDSALDH1A1HPGDPOLBRAB9A | |
| SCHEMBL1800622 | 0.79 | HPGDS (0.68) | HPGDSALDH1A1HPGDPOLBRAB9A | |
| SCHEMBL28380 | 0.79 | HPGDS (0.86) | HPGDSALDH1A1HPGDPOLBRAB9A | |
| SCHEMBL1799754 | 0.78 | ESR1 (0.49) | HPGDSALDH1A1HPGDPOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1911755-B1 | BENZOIMIDAZOLE COMPOUND CAPABLE OF INHIBITING PROSTAGLANDIN D SYNTHETASE | TAIHO PHARMACEUTICAL CO LTD (JP) | 2011-09-14 | — | — | EP | claimed |