Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28381 | 0.92 | HPGDS (1.00) | HPGDSALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL1799020 | 0.90 | HPGDS (0.69) | HPGDSALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL1800622 | 0.89 | HPGDS (0.68) | HPGDSALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL1800666 | 0.86 | HPGDS (0.63) | HPGDSALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL1800380 | 0.85 | HPGDS (0.63) | HPGDSALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL1797771 | 0.85 | HPGDS (0.65) | HPGDSKDRMEN1KMT2ACHEK2 | |
| SCHEMBL1799866 | 0.84 | HPGDS (0.61) | HPGDSALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL1799752 | 0.83 | HPGDS (0.61) | HPGDSALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL1802043 | 0.82 | HPGDS (0.59) | HPGDSALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL1799022 | 0.82 | HPGDS (0.82) | HPGDSALDH1A1HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782648-B1 | PROSTAGLANDIN D2 PRODUCTION INHIBITORS AS PREVENTATIVE AND THERAPEUTIC AGENTS FOR SARCOPENIA | NATIONAL UNIV CORPORATION TOKYO UNIV OF AGRICULTURE AND TECHNOLOGY (JP) | 2024-09-18 | — | — | EP | claimed |
| US-20210161908-A1 | PREVENTATIVE AND THERAPEUTIC AGENTS FOR SARCOPENIA | NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY (JP) | 2021-06-03 | — | — | US | claimed |
| EP-3782648-A1 | PREVENTATIVE AND THERAPEUTIC AGENTS FOR SARCOPENIA | National University Corporation Tokyo University of Agriculture and Technology (JP) | 2021-02-24 | — | — | EP | claimed |
| CN-111989119-A | Prophylactic and therapeutic agent for sarcopenia | 国立大学法人东京农工大学 | 2020-11-24 | — | — | CN | claimed |
| WO-2019203296-A1 | PREVENTATIVE AND THERAPEUTIC AGENTS FOR SARCOPENIA | 国立大学法人東京農工大学 | 2019-10-24 | — | — | WO | claimed |
| EP-1911755-B1 | BENZOIMIDAZOLE COMPOUND CAPABLE OF INHIBITING PROSTAGLANDIN D SYNTHETASE | TAIHO PHARMACEUTICAL CO LTD (JP) | 2011-09-14 | — | — | EP | claimed |
| US-7951956-B2 | Benzoimidazole compound capable of inhibiting prostaglandin D synthetase | TAIHO PHARMACEUTICALS CO., LTD. (JP) | 2011-05-31 | — | — | US | claimed |
| US-20090281098-A1 | BENZOIMIDAZOLE COMPOUND CAPABLE OF INHIBITING PROSTAGLANDIN D SYNTHETASE | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2009-11-12 | — | — | US | claimed |
| EP-1911755-A1 | BENZOIMIDAZOLE COMPOUND CAPABLE OF INHIBITING PROSTAGLANDIN D SYNTHETASE | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2008-04-16 | — | — | EP | claimed |
| EP-3782648-B1 | PROSTAGLANDIN D2 PRODUCTION INHIBITORS AS PREVENTATIVE AND THERAPEUTIC AGENTS FOR SARCOPENIA | NATIONAL UNIV CORPORATION TOKYO UNIV OF AGRICULTURE AND TECHNOLOGY (JP) | 2024-09-18 | — | — | EP | disclosed |
| US-11883410-B2 | Preventative and therapeutic agents for sarcopenia | NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLGY (JP) | 2024-01-30 | — | — | US | disclosed |
| US-20210161908-A1 | PREVENTATIVE AND THERAPEUTIC AGENTS FOR SARCOPENIA | NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY (JP) | 2021-06-03 | — | — | US | disclosed |
| WO-2021066136-A1 | THERAPEUTIC AGENT FOR MUSCULAR DYSTROPHY | 国立大学法人東京大学 | 2021-04-08 | — | — | WO | disclosed |
| EP-3782648-A1 | PREVENTATIVE AND THERAPEUTIC AGENTS FOR SARCOPENIA | National University Corporation Tokyo University of Agriculture and Technology (JP) | 2021-02-24 | — | — | EP | disclosed |
| US-7951956-B2 | Benzoimidazole compound capable of inhibiting prostaglandin D synthetase | TAIHO PHARMACEUTICALS CO., LTD. (JP) | 2011-05-31 | — | — | US | disclosed |
| US-20090281098-A1 | BENZOIMIDAZOLE COMPOUND CAPABLE OF INHIBITING PROSTAGLANDIN D SYNTHETASE | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2009-11-12 | — | — | US | disclosed |
| US-20090281098-A1 | BENZOIMIDAZOLE COMPOUND CAPABLE OF INHIBITING PROSTAGLANDIN D SYNTHETASE | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2009-11-12 | — | — | US | disclosed |
| US-20090281098-A1 | BENZOIMIDAZOLE COMPOUND CAPABLE OF INHIBITING PROSTAGLANDIN D SYNTHETASE | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2009-11-12 | — | — | US | disclosed |
| EP-1911755-A1 | BENZOIMIDAZOLE COMPOUND CAPABLE OF INHIBITING PROSTAGLANDIN D SYNTHETASE | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2008-04-16 | — | — | EP | disclosed |
| EP-1911755-A1 | BENZOIMIDAZOLE COMPOUND CAPABLE OF INHIBITING PROSTAGLANDIN D SYNTHETASE | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2008-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11883410-B2 | Preventative and therapeutic agents for sarcopenia | CPT1B, TNNC1, MTPN | HPGDS 32/4885ALDH1A1 1461/4885HPGD 23/4885 |
| US-20090281098-A1 | BENZOIMIDAZOLE COMPOUND CAPABLE OF INHIBITING PROSTAGLANDIN D SYNTHETASE | PTGS1, PTGIS, PTGES | HPGDS 5/4885ALDH1A1 368/4885HPGD 16/4885 |
| US-20210161908-A1 | PREVENTATIVE AND THERAPEUTIC AGENTS FOR SARCOPENIA | CPT1B, TNNC1, MTPN | HPGDS 32/4885ALDH1A1 1461/4885HPGD 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.