SCHEMBL24235261

SCHEMBL24235261

CCN1CC2(CC(=O)N(C)C2)C1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 2/20 0.39
CYP11B2 P19099 2/20 0.39
CRBN Q96SW2 1/20 0.37
TMEM97 Q5BJF2 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
CHRM2 P08172 1/20 0.33
CHRM3 P20309 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3477441 0.83 CYP11B1 (0.40) CYP11B1CYP11B2CRBNCHRM2CHRM3
SCHEMBL17485296 0.83 CYP11B1 (0.49) CYP11B1CYP11B2CRBNSIGMAR1CHRM2
SCHEMBL25664912 0.79 PIK3CD (0.47) CYP11B1CYP11B2CRBN
SCHEMBL14359443 0.79 CYP11B1 (0.43) CYP11B1CYP11B2CRBN
SCHEMBL18820444 0.78 TSHR (0.44) CYP11B1CYP11B2CRBNSIGMAR1CHRM2
SCHEMBL16189944 0.76
SCHEMBL26790423 0.73 CYP11B1 (0.38) CYP11B1CYP11B2CRBNCHRM2CHRM3
SCHEMBL25609376 0.72 CRHBP (0.37) CYP11B1CYP11B2CRBN
SCHEMBL24629789 0.72 CRBN (0.37) CYP11B1CYP11B2CRBN
SCHEMBL16609890 0.71 CRBN (0.39) CYP11B1CYP11B2CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022022600-A1 IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF BETTA PHARMACEUTICALS CO., LTD (CN) 2022-02-03 WO disclosed