Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18820444 | 0.88 | TSHR (0.44) | CYP11B1CYP11B2TSHRCRBNCHRM2 | |
| SCHEMBL26790423 | 0.87 | CYP11B1 (0.38) | CYP11B1CYP11B2TSHRCRBNCHRM2 | |
| SCHEMBL26850392 | 0.84 | TSHR (0.39) | CYP11B1CYP11B2TSHRCHRM2CHRM3 | |
| SCHEMBL24235261 | 0.83 | CYP11B1 (0.39) | CYP11B1CYP11B2CRBNCHRM2CHRM3 | |
| SCHEMBL3477441 | 0.82 | CYP11B1 (0.40) | CYP11B1CYP11B2TSHRCRBNCHRM2 | |
| SCHEMBL1753879 | 0.81 | CYP11B1 (0.50) | CYP11B1CYP11B2TSHRCRBNCHRM2 | |
| SCHEMBL16189944 | 0.80 | — | — | |
| SCHEMBL24994297 | 0.77 | CYP2D6 (0.55) | CYP11B1CYP11B2TSHRCHRM2CHRM3 | |
| SCHEMBL12832226 | 0.76 | CYP11B1 (0.46) | CYP11B1CYP11B2TSHRCRBNCHRM2 | |
| SCHEMBL24186788 | 0.75 | CYP11B1 (0.46) | CYP11B1CYP11B2CRBNLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230041621-A1 | SSTR5 ANTAGONISTS | KALLYOPE, INC. | 2023-02-09 | — | — | US | disclosed |
| US-20200163336-A1 | CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2020-05-28 | — | — | US | disclosed |
| WO-2016015604-A1 | COMPOUNDS AS CDK SMALL-MOLECULE INHIBITORS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-02-04 | — | — | WO | disclosed |
| WO-2016015605-A1 | COMPOUNDS AS CDK SMALL-MOLECULE INHIBITORS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230041621-A1 | SSTR5 ANTAGONISTS | SSTR5, GLP1R, GPR119 | CYP11B1 1217/4885CYP11B2 1009/4885TSHR 128/4885 |
| US-20200163336-A1 | CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT | H1-10, TAAR1, C5 | CYP11B1 2392/4885CYP11B2 2532/4885TSHR 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.