SCHEMBL24236409

SCHEMBL24236409

Cc1ccc(N(c2ccccc2)c2ccc3c(c2)C(C)(C)c2cc4cc(N(c5ccccc5)c5ccc(C)cc5)ccc4cc2-3)cc1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 5/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
HTT P42858 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TDP1 Q9NUW8 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
RARA P10276 1/20 0.32
RARB P10826 1/20 0.32
RARG P13631 1/20 0.32
CYP2A6 P11509 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18353785 0.95 PDK2 (0.38) PDK2L3MBTL1TDP1KDM4EALDH1A1
SCHEMBL17933083 0.95 HTT (0.32) L3MBTL1HTTNPSR1CYP1A2RARA
SCHEMBL22739758 0.93 L3MBTL1 (0.35) L3MBTL1HTTNPSR1TDP1KDM4E
SCHEMBL2606561 0.93 HTT (0.31) L3MBTL1HTTNPSR1RARARARB
SCHEMBL2606530 0.93 PDK2 (0.37) PDK2L3MBTL1TDP1KDM4EALDH1A1
SCHEMBL24236434 0.92 PDK2 (0.34) PDK2L3MBTL1TDP1KDM4EALDH1A1
SCHEMBL14499303 0.92 L3MBTL1 (0.42) PDK2L3MBTL1HTTNPSR1TDP1
SCHEMBL13341815 0.92 PDK2 (0.36) PDK2L3MBTL1HTTNPSR1TDP1
SCHEMBL19197163 0.92 L3MBTL1 (0.40) PDK2L3MBTL1HTTNPSR1TDP1
SCHEMBL23597995 0.91 PDK2 (0.41) PDK2L3MBTL1TDP1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220140247-A1 PLURALITY OF HOST MATERIALS, COMPOSITION COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-05-05 US disclosed
US-20220037596-A1 PLURALITY OF LIGHT-EMITTING MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2022-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220037596-A1 PLURALITY OF LIGHT-EMITTING MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, EML4, NECTIN4 PDK2 1625/4885L3MBTL1 43/4885HTT 1834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.