Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24239459 | 0.91 | POLB (0.31) | POLBGAA | |
| SCHEMBL24239455 | 0.89 | SERPINE1 (0.30) | SERPINE1 | |
| SCHEMBL8215989 | 0.75 | MMP1 (0.41) | SERPINE1 | |
| SCHEMBL99777 | 0.72 | SERPINE1 (0.34) | SERPINE1 | |
| SCHEMBL18963264 | 0.71 | HTT (0.37) | SERPINE1HTT | |
| SCHEMBL18908741 | 0.71 | MMP1 (0.37) | SERPINE1 | |
| SCHEMBL24239478 | 0.69 | HTT (0.40) | SERPINE1HTT | |
| SCHEMBL7228511 | 0.69 | SERPINE1 (0.33) | SERPINE1 | |
| SCHEMBL13123727 | 0.69 | MMP1 (0.37) | LMNA | |
| SCHEMBL24239460 | 0.68 | HTT (0.34) | POLBGAASERPINE1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220033340-A1 | METHODS | MEXICHEM FLUOR S.A. DE C.V. (MX) | 2022-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220033340-A1 | METHODS | CYP4F3, AOC3, ACOX3 | POLB 845/4885GAA 3758/4885SERPINE1 4865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.