Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 6/20 | 0.58 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.58 |
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.44 |
| ▸ | KDM5A | P29375 | 6/20 | 0.44 |
| ▸ | KDM4A | O75164 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24244248 | 0.81 | PHF8 (0.57) | PHF8KDM2BKDM4CKDM5BKDM5A | |
| SCHEMBL24244130 | 0.76 | KDM5A (0.66) | PHF8KDM2BKDM4CKDM5BKDM5A | |
| SCHEMBL29376220 | 0.73 | PHF8 (0.73) | PHF8KDM2BKDM4CKDM5BKDM5A | |
| SCHEMBL20979039 | 0.73 | KDM4C (0.57) | PHF8KDM2BKDM4CKDM5BKDM5A | |
| SCHEMBL17604577 | 0.73 | PHF8 (0.73) | PHF8KDM2BKDM4CKDM5BKDM5A | |
| SCHEMBL19383297 | 0.69 | PHF8 (0.62) | PHF8KDM2BKDM4CKDM5BKDM5A | |
| SCHEMBL24244136 | 0.69 | PHF8 (0.61) | PHF8KDM4CKDM5BKDM5AKDM4A | |
| SCHEMBL16033687 | 0.67 | KDM4C (0.61) | PHF8KDM2BKDM4CKDM5BKDM5A | |
| SCHEMBL24244200 | 0.66 | PHF8 (0.51) | PHF8KDM2BKDM4CKDM5BKDM5A | |
| SCHEMBL20979023 | 0.66 | KDM4C (0.57) | PHF8KDM2BKDM4CKDM5BKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193881-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2022-02-09 | — | — | EP | disclosed |