Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 9/20 | 0.66 |
| ▸ | KDM5B | Q9UGL1 | 8/20 | 0.66 |
| ▸ | KDM4C | Q9H3R0 | 11/20 | 0.52 |
| ▸ | KDM4A | O75164 | 5/20 | 0.52 |
| ▸ | PHF8 | Q9UPP1 | 6/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24244246 | 0.80 | KDM4C (0.68) | KDM5AKDM5BKDM4CKDM4APHF8 | |
| SCHEMBL16034016 | 0.79 | KDM5A (1.00) | KDM5AKDM5BKDM4CKDM4AKDM2B | |
| SCHEMBL19383404 | 0.78 | KDM4C (0.54) | KDM5AKDM5BKDM4CKDM4APHF8 | |
| SCHEMBL16034331 | 0.78 | KDM5B (0.77) | KDM5AKDM5BKDM4CKDM4APHF8 | |
| SCHEMBL19383523 | 0.76 | KDM5B (0.64) | KDM5AKDM5BKDM4CKDM4APHF8 | |
| SCHEMBL24244244 | 0.76 | PHF8 (0.58) | KDM5AKDM5BKDM4CKDM4APHF8 | |
| SCHEMBL24244248 | 0.75 | PHF8 (0.57) | KDM5AKDM5BKDM4CKDM4APHF8 | |
| SCHEMBL26208182 | 0.75 | KDM4C (0.73) | KDM5AKDM5BKDM4CKDM4APHF8 | |
| SCHEMBL26208206 | 0.75 | PHF8 (0.61) | KDM5AKDM5BKDM4CKDM4APHF8 | |
| SCHEMBL19101706 | 0.74 | KDM5A (0.67) | KDM5AKDM5BKDM4CKDM4APHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193881-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2022-02-09 | — | — | EP | disclosed |