Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29333409 | 0.93 | POLB (0.38) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL25933597 | 0.93 | POLB (0.38) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL24355953 | 0.93 | POLB (0.37) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL23643528 | 0.93 | POLB (0.38) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL25118254 | 0.89 | SRD5A2 (0.35) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL25943857 | 0.88 | POLB (0.36) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL17485637 | 0.85 | POLB (0.44) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL19881906 | 0.85 | TDP1 (0.34) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL23544524 | 0.85 | TDP1 (0.34) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL18511121 | 0.84 | POLB (0.38) | POLBAPEX1HTTTDP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3950670-A1 | POLYMERIZABLE COMPOUNDS | Merck Patent GmbH (DE) | 2022-02-09 | — | — | EP | disclosed |