Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28477000 | 0.83 | TLR7 (0.61) | TLR7NUDT1 | |
| SCHEMBL16206181 | 0.81 | TLR7 (1.00) | TLR7NUDT1 | |
| SCHEMBL18207658 | 0.80 | TLR7 (0.74) | TLR7NUDT1 | |
| SCHEMBL2913478 | 0.80 | TLR7 (0.74) | TLR7NUDT1 | |
| SCHEMBL3133950 | 0.79 | TLR7 (0.77) | TLR7NUDT1 | |
| SCHEMBL18207253 | 0.78 | TLR7 (0.71) | TLR7NUDT1 | |
| SCHEMBL3146807 | 0.78 | TLR7 (0.75) | TLR7NUDT1 | |
| SCHEMBL18221125 | 0.77 | TLR7 (1.00) | TLR7 | |
| SCHEMBL18207310 | 0.77 | TLR7 (0.65) | TLR7NUDT1 | |
| SCHEMBL3139086 | 0.77 | TLR7 (1.00) | TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11242345-B2 | Sulfonimidoylpurinone compounds and methods of treatment using the same | HOFFMANN-LA ROCHE INC. (US) | 2022-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11242345-B2 | Sulfonimidoylpurinone compounds and methods of treatment using the same | STS, SULT1E1, SULT1A1 | TLR7 2510/4885NUDT1 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.