Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.61 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.53 |
| ▸ | IL6 | P05231 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28675790 | 0.92 | TLR7 (0.60) | TLR7 | |
| SCHEMBL28428260 | 0.88 | TLR7 (0.64) | TLR7 | |
| SCHEMBL28417397 | 0.88 | TLR7 (0.59) | TLR7IL6 | |
| SCHEMBL28428146 | 0.87 | TLR7 (0.62) | TLR7IL6 | |
| SCHEMBL28424659 | 0.86 | TLR7 (0.63) | TLR7 | |
| SCHEMBL28422647 | 0.86 | TLR7 (0.63) | TLR7 | |
| SCHEMBL28426046 | 0.85 | TLR7 (0.62) | TLR7IL6 | |
| SCHEMBL24246019 | 0.83 | TLR7 (0.68) | TLR7NUDT1 | |
| SCHEMBL28420561 | 0.81 | TLR7 (0.38) | TLR7IL6 | |
| SCHEMBL16206181 | 0.77 | TLR7 (1.00) | TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641904-B | 7-substituted sulfoxy-purinone compounds for the treatment and prevention of viral infections | 豪夫迈·罗氏有限公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-111801100-A | 7-substituted sulfoxy-purinone compounds and derivatives for the treatment and prevention of liver cancer | 豪夫迈·罗氏有限公司 | 2020-10-20 | — | — | CN | disclosed |