Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23106893 | 1.00 | HMGCR (0.33) | HMGCRALOX5PTGS2CYP19A1PLA2G2A | |
| SCHEMBL24246323 | 0.74 | CYP19A1 (0.33) | CYP19A1 | |
| SCHEMBL23106983 | 0.74 | CYP19A1 (0.33) | CYP19A1 | |
| SCHEMBL23106927 | 0.69 | SMN1; SMN2 (0.34) | CYP19A1 | |
| SCHEMBL24246204 | 0.69 | SMN1; SMN2 (0.34) | CYP19A1 | |
| SCHEMBL23106956 | 0.69 | SMN1; SMN2 (0.34) | CYP19A1 | |
| SCHEMBL23107237 | 0.63 | MAPT (0.47) | PTGS2 | |
| SCHEMBL12620337 | 0.63 | MAPT (0.42) | PTGS2 | |
| SCHEMBL24246322 | 0.63 | MAPT (0.47) | PTGS2 | |
| SCHEMBL23106867 | 0.62 | SHBG (0.44) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3634954-B1 | METHOD OF PRODUCING EPD AND ANALOGUES THEREOF | VAN HAAFTEN CAROLINE (NL) | 2022-02-09 | — | — | EP | disclosed |