Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 11/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13833222 | 0.88 | HPGD (0.97) | HPGDL3MBTL1ALDH1A1HSD17B10HTT | |
| SCHEMBL2026474 | 0.87 | HPGD (1.00) | HPGDL3MBTL1ALDH1A1HSD17B10HTT | |
| SCHEMBL5157052 | 0.77 | HTT (0.84) | HPGDALDH1A1HTTDRD4HTR1A | |
| SCHEMBL5663240 | 0.77 | HPGD (0.63) | HPGDL3MBTL1ALDH1A1HSD17B10HTT | |
| SCHEMBL12045417 | 0.74 | HTT (0.97) | HPGDALDH1A1HSD17B10HTTDRD4 | |
| SCHEMBL29368802 | 0.74 | HTT (0.97) | HPGDALDH1A1HSD17B10HTTDRD4 | |
| SCHEMBL5412340 | 0.73 | HTT (0.73) | HPGDALDH1A1HTTDRD4HTR1A | |
| SCHEMBL7704542 | 0.73 | HPGD (0.64) | HPGDL3MBTL1ALDH1A1HSD17B10HTT | |
| SCHEMBL15063202 | 0.73 | HTT (1.00) | HPGDALDH1A1HSD17B10HTTDRD4 | |
| SCHEMBL31010306 | 0.73 | HTT (1.00) | HPGDALDH1A1HSD17B10HTTDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11246949-B2 | Imaging contrast agents and uses thereof | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11246949-B2 | Imaging contrast agents and uses thereof | SLC40A1, SLC39A14, SLC39A3 | HPGD 327/4885L3MBTL1 1496/4885ALDH1A1 4328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.