Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.84 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.71 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.71 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | MELK | Q14680 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24247586 | 0.89 | HDAC1 (0.69) | MAPTHDAC1HDAC8HDAC6HDAC11 | |
| SCHEMBL24031181 | 0.87 | THRB (0.71) | MAPTHDAC1HDAC8HDAC6HDAC11 | |
| SCHEMBL24247595 | 0.87 | HDAC1 (0.71) | MAPTHDAC1HDAC8HDAC6HDAC11 | |
| SCHEMBL24247588 | 0.87 | HDAC1 (0.71) | MAPTHDAC1HDAC8HDAC6HDAC11 | |
| SCHEMBL24247607 | 0.86 | HDAC1 (0.73) | MAPTHDAC1HDAC8HDAC6HDAC11 | |
| SCHEMBL24030756 | 0.83 | HDAC6 (1.00) | MAPTHDAC1HDAC8HDAC6HDAC11 | |
| SCHEMBL29382979 | 0.83 | HDAC6 (1.00) | MAPTHDAC1HDAC8HDAC6HDAC11 | |
| SCHEMBL16674525 | 0.82 | TSHR (0.73) | MAPTHDAC1HDAC8HDAC6HDAC11 | |
| SCHEMBL30317689 | 0.76 | HDAC6 (0.74) | MAPTHDAC1HDAC8HDAC6HDAC11 | |
| SCHEMBL24031180 | 0.75 | MAPT (0.70) | MAPTHDAC1HDAC8HDAC6HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3624804-B1 | HISTONE DEACETYLASES (HDACS) INHIBITORS | ANNJI PHARM CO LTD (TW) | 2022-02-16 | — | — | EP | disclosed |