Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2423208 | 0.79 | — | — | |
| SCHEMBL5270457 | 0.71 | — | — | |
| SCHEMBL2451086 | 0.68 | CYP24A1 (0.38) | P2RX4BCHETSHRGPR119 | |
| SCHEMBL23407929 | 0.64 | NOS1 (0.44) | P2RX4BCHETSHR | |
| SCHEMBL1427720 | 0.64 | P2RX4 (0.37) | P2RX4BCHETSHRJMJD6GPR119 | |
| SCHEMBL23418624 | 0.63 | P2RX4 (0.42) | P2RX4BCHETSHR | |
| SCHEMBL751362 | 0.63 | P2RX4 (0.33) | P2RX4BCHETSHR | |
| SCHEMBL753376 | 0.63 | P2RX4 (0.33) | P2RX4BCHETSHR | |
| SCHEMBL162055 | 0.62 | BCHE (0.38) | P2RX4BCHETSHRJMJD6GPR119 | |
| SCHEMBL26317513 | 0.62 | TSHR (0.43) | P2RX4BCHETSHRGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1605752-B1 | Sulfonamides for the treatment of congestive heart failure, their compositions and uses. | CYTOKINETICS INC (US) | 2011-09-14 | — | — | EP | disclosed |