Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1427724 | 0.78 | — | — | |
| SCHEMBL29299953 | 0.75 | NOTUM (0.33) | NOTUM | |
| SCHEMBL6784600 | 0.74 | LPO (0.37) | TSHRALDH1A1HPGD | |
| SCHEMBL23407929 | 0.73 | NOS1 (0.44) | P2RX4TSHRBCHE | |
| SCHEMBL8136815 | 0.73 | FAAH (0.36) | BCHEGPR119SMN1; SMN2 | |
| SCHEMBL876240 | 0.72 | — | — | |
| SCHEMBL166053 | 0.71 | FOLH1 (0.32) | CYP19A1 | |
| SCHEMBL4971138 | 0.69 | P2RX4 (0.35) | P2RX4BCHE | |
| SCHEMBL30666200 | 0.69 | SMN1; SMN2 (0.36) | ALDH1A1SMN1; SMN2NOTUM | |
| SCHEMBL24328029 | 0.69 | PKM (0.34) | P2RX4BCHESMN1; SMN2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300470-A2 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS GABA-A RECEPTOR MODULATORS | Sepracor Inc. (US) | 2011-03-30 | — | — | EP | disclosed |