Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | TLR4 | O00206 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 8/20 | 0.35 |
| ▸ | CES1 | P23141 | 5/20 | 0.34 |
| ▸ | CES2 | O00748 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12091326 | 0.93 | CES2 (0.33) | CYP1A2TLR4FAAHCES1CES2 | |
| SCHEMBL22139465 | 0.93 | CES2 (0.33) | CYP1A2TLR4FAAHCES1CES2 | |
| SCHEMBL2693722 | 0.76 | CYP1A2 (0.50) | CYP1A2TLR4MEN1KMT2AMAPT | |
| SCHEMBL6526063 | 0.76 | CYP1A2 (0.50) | CYP1A2TLR4MEN1KMT2AMAPT | |
| SCHEMBL18965394 | 0.76 | CYP1A2 (0.34) | CYP1A2TLR4CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL18414331 | 0.76 | CYP1A2 (0.34) | CYP1A2TLR4CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL2691363 | 0.75 | CYP1A2 (0.58) | CYP1A2TLR4MEN1KMT2ACYP3A4 | |
| SCHEMBL18965607 | 0.74 | CYP1A2 (0.46) | CYP1A2FAAHCES1CES2MEN1 | |
| SCHEMBL24248131 | 0.74 | CYP1A2 (0.33) | CYP1A2TLR4MAPT | |
| SCHEMBL20822215 | 0.73 | CYP1A2 (0.56) | CYP1A2TLR4MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3594201-B1 | PROCESS FOR THE PREPARATION OF LUBIPROSTONE AND INTERMEDIATES THEREOF | CHIROGATE INT INC (TW) | 2022-02-16 | — | — | EP | disclosed |