SCHEMBL18414331

SCHEMBL18414331

CCCCC(F)(F)C(O)(O)CC[C@H]1CCC(=O)C1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.34
TLR4 O00206 1/20 0.32
NOS1 P29475 2/20 0.31
NOS2 P35228 2/20 0.31
CYP3A4 P08684 1/20 0.30
CYP2C8 P10632 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
S1PR3 Q99500 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18965394 1.00 CYP1A2 (0.34) CYP1A2TLR4NOS1NOS2CYP3A4
SCHEMBL18965550 0.85 CYP1A2 (0.32) CYP1A2CYP3A4CYP2C8CYP2D6CYP2C9
SCHEMBL12091326 0.77 CES2 (0.33) CYP1A2TLR4
SCHEMBL22139465 0.77 CES2 (0.33) CYP1A2TLR4
SCHEMBL24248131 0.76 CYP1A2 (0.33) CYP1A2TLR4
SCHEMBL24248166 0.76 CYP1A2 (0.35) CYP1A2TLR4CYP3A4CYP2C8CYP2D6
SCHEMBL2693722 0.75 CYP1A2 (0.50) CYP1A2TLR4NOS1NOS2
SCHEMBL6526063 0.75 CYP1A2 (0.50) CYP1A2TLR4NOS1NOS2
SCHEMBL2691363 0.73 CYP1A2 (0.58) CYP1A2TLR4NOS1NOS2CYP3A4
SCHEMBL20822308 0.72 CYP1A2 (0.56) CYP1A2TLR4NOS1NOS2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170020890-A1 PHARMACEUTICAL COMPOSITION COMPRISING FATTY ACID DERIVATIVE SUCAMPO AG (CH) 2017-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170020890-A1 PHARMACEUTICAL COMPOSITION COMPRISING FATTY ACID DERIVATIVE SCD, FASN, SCD5 CYP1A2 334/4885TLR4 2556/4885NOS1 4134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.