Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3305728 | 0.87 | NFE2L2 (0.64) | SMN1; SMN2MAPTNFE2L2RAB9ANPC1 | |
| SCHEMBL3305717 | 0.87 | NFE2L2 (0.64) | SMN1; SMN2MAPTNFE2L2RAB9ANPC1 | |
| SCHEMBL3305722 | 0.87 | NFE2L2 (0.64) | SMN1; SMN2MAPTNFE2L2RAB9ANPC1 | |
| SCHEMBL11710569 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTNFE2L2GPR52ERCC5 | |
| SCHEMBL9101487 | 0.80 | CYP1A1 (0.50) | PTPN1GSK3BCYP1A1CYP1B1 | |
| SCHEMBL8512571 | 0.80 | CYP1A1 (0.50) | PTPN1GSK3BCYP1A1CYP1B1 | |
| SCHEMBL3306429 | 0.79 | LMNA (0.55) | NFE2L2GPR52MEN1KMT2AL3MBTL1 | |
| SCHEMBL3306434 | 0.79 | LMNA (0.55) | NFE2L2GPR52MEN1KMT2AL3MBTL1 | |
| SCHEMBL3306440 | 0.79 | LMNA (0.55) | NFE2L2GPR52MEN1KMT2AL3MBTL1 | |
| SCHEMBL4929674 | 0.78 | NFE2L2 (0.70) | SMN1; SMN2MAPTNFE2L2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048925-A1 | Substituted 3,4,12,12a-Tetrahydro-1H-[1,4]Oxazino[3,4-c]Pyrido[2,1-f][1,2,4]Triazine-6,8-dione, Pharmaceutical Composition, Method for the Production and Use Thereof | VIRIOM, INC. | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048925-A1 | Substituted 3,4,12,12a-Tetrahydro-1H-[1,4]Oxazino[3,4-c]Pyrido[2,1-f][1,2,4]Triazine-6,8-dione, Pharmaceutical Composition, Method for the Production and Use Thereof | H1-3, H1-5, H1-0 | SMN1; SMN2 590/4885MAPT 2466/4885NFE2L2 3962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.