Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.61 |
| ▸ | RAB9A | P51151 | 10/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | AR | P10275 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.60 |
| ▸ | RELA | Q04206 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | GMNN | O75496 | 1/20 | 0.59 |
| ▸ | THPO | P40225 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30847671 | 1.00 | NPC1 (0.61) | NPC1RAB9AMEN1KMT2AAR | |
| SCHEMBL14278925 | 0.86 | RAB9A (0.61) | NPC1RAB9AMEN1KMT2AAR | |
| SCHEMBL28898945 | 0.85 | NPC1 (0.46) | NPC1RAB9AMEN1KMT2AAR | |
| SCHEMBL12112870 | 0.84 | RAB9A (0.80) | NPC1RAB9AMEN1KMT2AAR | |
| SCHEMBL20089432 | 0.84 | NPC1 (0.51) | NPC1RAB9AMEN1KMT2AAR | |
| SCHEMBL18858303 | 0.84 | RAB9A (0.51) | NPC1RAB9AMEN1KMT2AAR | |
| SCHEMBL17413737 | 0.83 | RAB9A (0.47) | NPC1RAB9AMEN1KMT2AAR | |
| SCHEMBL29544777 | 0.82 | NPC1 (0.62) | NPC1RAB9AMEN1KMT2AAR | |
| SCHEMBL22734790 | 0.82 | NPC1 (0.62) | NPC1RAB9AMEN1KMT2AAR | |
| SCHEMBL16021662 | 0.82 | ESR1 (0.51) | NPC1RAB9AMEN1KMT2AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104910079-B | The method that toluene and derivative oxidation one kettle way prepare 4 (3H) Quinazol derivatives | 同济大学 | 2017-08-25 | — | — | CN | disclosed |
| US-20140378685-A1 | PREPARATION OF HETEROLEPTIC METAL COMPLEXES | SOLVAY SA (BE) | 2014-12-25 | — | — | US | disclosed |
| US-8680760-B2 | Beta-diketone ancillary ligands and their metal complexes used in organic optoelectronic devices | NATIONAL TSING HUA UNIVERSITY (TW) | 2014-03-25 | — | — | US | disclosed |
| US-20130331577-A1 | PREPARATION OF A FAC-ISOMER FOR A TRIS HOMOLEPTIC METAL COMPLEX | SOLVAY SA | 2013-12-12 | — | — | US | disclosed |
| EP-2665735-A1 | PREPARATION OF A FAC-ISOMER FOR A TRIS HOMOLEPTIC METAL COMPLEX | SOLVAY SA (BE) | 2013-11-27 | — | — | EP | disclosed |
| CN-103298822-A | Preparation of a fac-isomer for a tris homoleptic metal complex | SOLVAY | 2013-09-11 | — | — | CN | disclosed |
| WO-2013098189-A1 | PREPARATION OF HETEROLEPTIC METAL COMPLEXES | SOLVAY SA (BE) | 2013-07-04 | — | — | WO | disclosed |
| EP-1902076-B1 | LIGHT EMITTING POLYMER MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE AND DISPLAY DEVICE COMPRISING LIGHT EMITTING POLYMER MATERIAL | SHOWA DENKO KK (JP) | 2012-11-21 | — | — | EP | disclosed |
| WO-2012084219-A1 | PREPARATION OF A FAC-ISOMER FOR A TRIS HOMOLEPTIC METAL COMPLEX | SOLVAY SA (BE) | 2012-06-28 | — | — | WO | disclosed |
| US-8025987-B2 | Light emitting polymer material, organic electroluminescence device and display device comprising light emitting polymer material | SHOWA DENKO K.K. (JP) | 2011-09-27 | — | — | US | disclosed |
| US-20100270915-A1 | Beta-Diketone Ancillary Ligands and Their Metal Complexes Used in Organic Optoelectronic Devices | NATIONAL TSING HUA UNIVERSITY (TW) | 2010-10-28 | — | — | US | disclosed |
| US-20100270915-A1 | Beta-Diketone Ancillary Ligands and Their Metal Complexes Used in Organic Optoelectronic Devices | NATIONAL TSING HUA UNIVERSITY (TW) | 2010-10-28 | — | — | US | disclosed |
| US-20090096353-A1 | LIGHT EMITTING POLYMER MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE AND DISPLAY DEVICE COMPRISING LIGHT EMITTING POLYMER MATERIAL | SHOWA DENKO K.K. (JP) | 2009-04-16 | — | — | US | disclosed |
| EP-1902076-A1 | LIGHT EMITTING POLYMER MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE AND DISPLAY DEVICE COMPRISING LIGHT EMITTING POLYMER MATERIAL | Showa Dendo K.K. (JP) | 2008-03-26 | — | — | EP | disclosed |
| WO-2006135076-A1 | LIGHT EMITTING POLYMER MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE AND DISPLAY DEVICE COMPRISING LIGHT EMITTING POLYMER MATERIAL | SHOWA DENKO K.K. (JP) | 2006-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100270915-A1 | Beta-Diketone Ancillary Ligands and Their Metal Complexes Used in Organic Optoelectronic Devices | PBK, DEK, OSTC | NPC1 4443/4885RAB9A 4435/4885MEN1 4347/4885 |
| US-20130331577-A1 | PREPARATION OF A FAC-ISOMER FOR A TRIS HOMOLEPTIC METAL COMPLEX | FHIT, AP2M1, AP1M1 | NPC1 1803/4885RAB9A 2336/4885MEN1 674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.