Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 2/20 | 0.34 |
| ▸ | CCND1 | P24385 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24251326 | 1.00 | CDK4 (0.34) | CDK4CCND1ESR1ESR2BACE1 | |
| SCHEMBL24251338 | 1.00 | CDK4 (0.34) | CDK4CCND1ESR1ESR2BACE1 | |
| SCHEMBL24251325 | 1.00 | CDK4 (0.34) | CDK4CCND1ESR1ESR2BACE1 | |
| SCHEMBL12575566 | 0.95 | CYP1A2 (0.33) | CDK4CCND1ERBB2CYP1A2FYN | |
| SCHEMBL18810724 | 0.95 | CYP1A2 (0.34) | CDK4CCND1ESR1ESR2BACE1 | |
| SCHEMBL24251343 | 0.94 | CDK4 (0.34) | CDK4CCND1ESR1ESR2BACE1 | |
| SCHEMBL24251328 | 0.94 | CDK4 (0.32) | CDK4CCND1NPC1 | |
| SCHEMBL12575630 | 0.93 | MEN1 (0.38) | CDK4CCND1NPC1 | |
| SCHEMBL12575666 | 0.93 | PTGDR2 (0.33) | CDK4CCND1CYP1A2 | |
| SCHEMBL24251341 | 0.93 | CDK4 (0.35) | CDK4CCND1ESR1ESR2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220052263-A1 | AMINE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG ELECTRONICS CO., LTD., (KR) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220052263-A1 | AMINE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | AOC2, ODC1, AOC1 | CDK4 2021/4885CCND1 498/4885ESR1 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.