Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23942920 | 0.88 | AGTR2 (0.53) | MMP9AGTR2TMEM97CARM1PRMT6 | |
| SCHEMBL26207194 | 0.88 | AGTR2 (0.53) | MMP9AGTR2TMEM97CARM1PRMT6 | |
| SCHEMBL14597374 | 0.86 | AGTR2 (0.46) | MMP9AGTR2TMEM97CARM1PRMT6 | |
| SCHEMBL9969601 | 0.86 | AGTR2 (0.46) | MMP9AGTR2TMEM97CARM1PRMT6 | |
| SCHEMBL8290842 | 0.86 | AGTR2 (0.46) | MMP9AGTR2TMEM97CARM1PRMT6 | |
| SCHEMBL19181066 | 0.86 | MMP9 (0.47) | MMP9AGTR2BACE1CYP2C19 | |
| SCHEMBL29385791 | 0.86 | AGTR2 (0.46) | MMP9AGTR2MMP2CTSLCTSB | |
| SCHEMBL21751203 | 0.86 | MMP9 (0.47) | MMP9AGTR2BACE1CYP2C19 | |
| SCHEMBL13729227 | 0.86 | AGTR2 (0.46) | MMP9AGTR2MMP2CTSLCTSB | |
| SCHEMBL13613076 | 0.83 | POLB (0.48) | AGTR2BDKRB2CPB1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4169922-A1 | FGFR AND MUTATION INHIBITOR THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2023-04-26 | — | — | EP | disclosed |
| WO-2022033532-A1 | FGFR AND MUTATION INHIBITOR THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海和誉生物医药科技有限公司 | 2022-02-17 | — | — | WO | disclosed |