Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21884189 | 0.98 | CES2 (0.35) | CES2LPAR1LPAR3 | |
| SCHEMBL21470295 | 0.98 | CES2 (0.33) | CES2LPAR1LPAR3 | |
| SCHEMBL19628911 | 0.96 | CES2 (0.36) | CES2LPAR1LPAR3 | |
| SCHEMBL19879718 | 0.93 | CES2 (0.34) | CES2LPAR1LPAR3 | |
| SCHEMBL19731420 | 0.89 | CES2 (0.31) | CES2LPAR1LPAR3 | |
| SCHEMBL22624049 | 0.89 | — | — | |
| SCHEMBL22624147 | 0.82 | — | — | |
| SCHEMBL22623884 | 0.80 | — | — | |
| SCHEMBL22624022 | 0.77 | CES2 (0.32) | CES2LPAR1LPAR3 | |
| SCHEMBL21191697 | 0.76 | CES2 (0.38) | CES2LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048915-A1 | Nitrogen-containing Heterocyclic Compound and Composition Thereof, Preparation Method Therefor, and Application Thereof | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048915-A1 | Nitrogen-containing Heterocyclic Compound and Composition Thereof, Preparation Method Therefor, and Application Thereof | MAPK11, WEE1, NOS1 | CES2 4408/4885LPAR1 4032/4885LPAR3 4383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.