Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | HTR2B | P41595 | 4/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252041 | 0.83 | HTR2C (0.34) | HTR2AHTR2CHTR2BFFAR1CES2 | |
| SCHEMBL17186941 | 0.75 | ELANE (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL17186806 | 0.73 | PPARA (0.47) | CES2CES1 | |
| SCHEMBL802723 | 0.70 | HTR2A (0.44) | HTR2AHTR2CHTR2B | |
| SCHEMBL15738889 | 0.69 | FFAR1 (0.32) | FFAR1 | |
| SCHEMBL15512399 | 0.69 | CES2 (0.39) | HTR2AHTR2CHTR2BFFAR1CES2 | |
| SCHEMBL15736497 | 0.68 | FFAR1 (0.31) | FFAR1 | |
| SCHEMBL15738365 | 0.68 | FFAR1 (0.31) | FFAR1 | |
| SCHEMBL15735867 | 0.68 | FFAR1 (0.31) | FFAR1 | |
| SCHEMBL13748809 | 0.68 | HTR2A (0.44) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048915-A1 | Nitrogen-containing Heterocyclic Compound and Composition Thereof, Preparation Method Therefor, and Application Thereof | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048915-A1 | Nitrogen-containing Heterocyclic Compound and Composition Thereof, Preparation Method Therefor, and Application Thereof | MAPK11, WEE1, NOS1 | HTR2A 4415/4885HTR2C 3134/4885HTR2B 3455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.