Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30857462 | 1.00 | DHODH (0.56) | DHODHCYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL17369027 | 0.94 | DHODH (0.56) | DHODHCYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL22763782 | 0.94 | DHODH (0.56) | DHODHCYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL17918062 | 0.92 | CYP11B2 (0.62) | DHODHCYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL17013859 | 0.90 | DHODH (0.53) | DHODHCYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL24252241 | 0.90 | DHODH (0.53) | DHODHCYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL24252718 | 0.90 | DHODH (0.53) | DHODHCYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL17369026 | 0.90 | DHODH (0.53) | DHODHCYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL24252236 | 0.90 | DHODH (0.53) | DHODHCYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL19486524 | 0.89 | CYP19A1 (0.54) | DHODHCYP19A1CYP11B1CYP11B2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654611-B | Compound having pyrimidine ring structure and organic electroluminescent element | 保土谷化学工业株式会社 | 2024-04-30 | — | — | CN | disclosed |
| US-20220052268-A1 | COMPOUND HAVING PYRIMIDINE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENT ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2022-02-17 | — | — | US | disclosed |
| CN-112654611-A | Compound having pyrimidine ring structure and organic electroluminescent element | 保土谷化学工业株式会社 | 2021-04-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220052268-A1 | COMPOUND HAVING PYRIMIDINE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENT ELEMENT | SLC29A1, NUDT1, SLC29A2 | DHODH 202/4885CYP19A1 2810/4885CYP11B1 4052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.